N,N-Diethylethylenediamine

N,N-Diethylethylenediamine Basic information
Product Name:N,N-Diethylethylenediamine
Synonyms:DEAEA;(DIETHYLAMINO)ETHYLAMINE;BETA-DIETHYLAMINOETHYLAMINE;1-AMINO-2-(DIETHYLAMINO)ETHANE;2-(DIETHYLAMINO)ETHYLAMINE;2-aminoethyldiethylamine;(Diethylamino)ethylamino;1-Amino-2-(N,N-diethylamino)ethane
CAS:100-36-7
MF:C6H16N2
MW:116.2
EINECS:202-844-7
Product Categories:synthetic organic intermediate;1;bc0001;K00001
Mol File:100-36-7.mol
N,N-Diethylethylenediamine Structure
N,N-Diethylethylenediamine Chemical Properties
Melting point <-70°C
Boiling point 145-147 °C(lit.)
density 0.827 g/mL at 25 °C(lit.)
vapor pressure 5.33hPa at 20℃
refractive index n20/D 1.436(lit.)
Fp 87 °F
storage temp. Store below +30°C.
solubility soluble in Methanol, Water
form Liquid
pkapK1:7.70(+2);pK2:10.46(+1) (25°C)
color Clear colorless to light yellow
explosive limit0.7-8.4%(V)
Water Solubility MISCIBLE
Sensitive Air Sensitive
BRN 605299
InChIKeyPQZTVWVYCLIIJY-UHFFFAOYSA-N
LogP0.1 at 25℃
CAS DataBase Reference100-36-7(CAS DataBase Reference)
NIST Chemistry Reference1,2-Ethanediamine, N,N-diethyl-(100-36-7)
EPA Substance Registry SystemN,N-Diethylethylenediamine (100-36-7)
Safety Information
Hazard Codes C,Xi
Risk Statements 10-20/21/22-35-21-36/37/38-34
Safety Statements 26-36/37/39-45-25-16-36-27
RIDADR UN 2685 8/PG 2
WGK Germany 1
RTECS KV3500000
Autoignition Temperature245 °C
TSCA Yes
HazardClass 8
PackingGroup II
HS Code 29212900
ToxicityLD50 orally in Rabbit: 984 mg/kg LD50 dermal Rabbit 820 mg/kg
MSDS Information
ProviderLanguage
2-Aminoethyldiethylamine English
SigmaAldrich English
ACROS English
ALFA English
N,N-Diethylethylenediamine Usage And Synthesis
Chemical PropertiesCLEAR COLORLESS TO LIGHT YELLOW LIQUID
UsesN,N-Diethylethylenediamine is used in the syntheses of anti-malarials. In addition, it has been seem to induce apoptosis through a caspase-3 dependent pathway.
UsesN,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.
Flammability and ExplosibilityFlammable
Safety ProfilePoison by intraperitoneal route. Moderately toxic by ingestion and skin contact. A slun and severe eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
2-Aminoethyl(ethyl)amine N,N-Diethylethylenediamine N,N,N',N'-Tetramethylethylenediamine 2-Aminoethylammonium chloride N,N,N',N'-TETRAKIS(2-HYDROXYETHYL)ETHYLENEDIAMINE 2-Aminoethyldiisopropylamine Diethyl oxalate 2-(2-Aminoethylamino)ethanol N-(1-Naphthyl)ethylenediamine dihydrochloride Diethyl ether Mefenpyr-diethyl N,N-Dimethylethylenediamine 1-(2-Aminoethyl)pyrrolidine 1,2-Cyclohexylenedinitrilotetraacetic acid Lysergic acid diethylamide Celiprolol Actinomycin D Ethylene glycol diethyl ether

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