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| | Triethylene glycol Basic information |
| | Triethylene glycol Chemical Properties |
| Melting point | −7 °C(lit.) | | Boiling point | 125-127 °C0.1 mm Hg(lit.) | | density | 1.124 g/mL at 20 °C(lit.) | | vapor density | 5.2 (vs air) | | vapor pressure | <0.01 mm Hg ( 20 °C) | | refractive index | n20/D 1.455(lit.) | | Fp | 165 °C | | storage temp. | Store below +30°C. | | solubility | H2O: 50 mg/mL at 20 °C, clear, colorless | | form | Viscous Liquid | | pKa | 14.06±0.10(Predicted) | | color | Clear very slightly yellow | | Odor | Very mild, sweet. | | PH | 5.5-7.0 (25℃, 50mg/mL in H2O) | | explosive limit | 0.9-9.2%(V) | | Water Solubility | SOLUBLE | | λmax | λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03 | | Sensitive | Hygroscopic | | Merck | 14,9670 | | BRN | 969357 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | ZIBGPFATKBEMQZ-UHFFFAOYSA-N | | LogP | -1.75 at 25℃ | | CAS DataBase Reference | 112-27-6(CAS DataBase Reference) | | NIST Chemistry Reference | Triethylene glycol(112-27-6) | | EPA Substance Registry System | Triethylene glycol (112-27-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 1 | | RTECS | YE4550000 | | Autoignition Temperature | 699 °F | | TSCA | Yes | | HS Code | 29094919 | | Hazardous Substances Data | 112-27-6(Hazardous Substances Data) | | Toxicity | LD50 in mice, rats (g/kg): 21, 15-22 orally; 7.3-9.5, 11.7 i.v. (Stenger) |
| | Triethylene glycol Usage And Synthesis |
| Description | Triethylene Glycol (TEG) is the third members of a homologous series of dihydroxyalcohols. TEG is produced in the Master Process by the direct hydration of ethylene oxide. TEG is co-produced with MEG and DEG. TEG is a colourless liquid.
The main uses for triethylene glycol are based upon its hygroscopic quality. It is used as a dehydrating agent for natural gas pipelines where it removes the water from the gas before being condensed and reused in the system. It is also a dehumidifying agent in air-conditioning units.
It is also used to make chemical intermediates such as plasticisers and polyester resins. It is an additive in hydraulic fluids and brake fluids, and TEG is also used as a solvent in many applications, including as a selective solvent for aromatics, and a solvent in textile dyeing.
Triethylene glycol also has mild disinfectant qualities and, when volatised, is used as an air disinfectant for virus and bacteria control. | | Chemical Properties | Triethylene glycol is a clear, colorless, viscous, stable liquid with a slightly sweetish odor. Soluble in water; immiscible with benzene, toluene, and gasoline. Combustible. Because it has two ether and two hydroxyl groups its chemical properties are closety related to ethers and primary alcohols. It is a good solvent for gums, resins, nitrocellulose, steam-set printing inks and wood stains. With a low vapor pressure and a high boiling point, its uses and properties are similar to those of ethylene glycol and diethylene glycol. Because it is an efficient hygroscopic agent it serves as a liquid desiccant for removing water from natural gas. It is also used in air conditioning systems designed to dehumidify air.
| | Uses | triethylene glycol is a solvent prepared from ethylene oxide and ethylene glycol.
Triethylene glycol can be used:
To prepare fatty acid gelators, which are used to gelate various edible and vegetable oils.
As a solvent to prepare superparamagnetic iron oxide nanoparticles for in situ protein purification.
As an absorbent agent in the subsea natural gas dehydration process. | | Uses | In various plastics to increase pliability; in air disinfection. | | Uses | Triethylene glycol is used as a plasticizer, as an additive for hydraulic fluids and brake fluids, and as a disinfectant. It is an active component of certain pigments, printing dyes, inks and paste. It finds application as a liquid desiccant and used in the dehydration of natural gas, carbon dioxide, hydrogen sulfide and air conditioning systems. It plays as an important role in anti-freeze and de-icing products, cleaning and furnishing care products, lubricant and greases. | | Uses | Triethylene glycol is widely used as an excellent dehydrating agent for natural gas, oilfield associated gas and carbon dioxide; Used as solvent for nitrocellulose, rubber, resin, grease, paint, pesticide, etc; Used as air bactericide; Used as triethylene glycol ester plasticizer for PVC, polyvinyl acetate resin, glass fiber and asbestos pressing board; Used as anti drying agent of tobacco, fiber lubricant and desiccant of natural gas; It is also used in organic synthesis, such as the production of brake oil with high boiling point and good low temperature performance. It can be used in gas chromatography as extractant. | | Definition | ChEBI: A poly(ethylene glycol) that is octane-1,8-diol in which the carbon atoms at positions 3 and 6 have been replaced by oxygen atoms. | | Production Methods | Triethylene glycol, like diethylene glycol, is produced commercially
as a by-product of ethylene glycol production.
Its formation is favored by a high ethylene oxide to water
ratio. | | General Description | Colorless liquid with a mild odor. Dense than water. | | Reactivity Profile | Triethylene glycol is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Reacts with strong oxidants. [Handling Chemicals Safely 1980. p. 932]. | | Health Hazard | Under normal conditions of use, Triethylene Glycol (TEG) is not expected to cause irritation to the skin, eyes or respiratory tract. However, in applications where vapours or mists are created, inhalation may cause irritation to the respiratory system.
No ceiling on worker exposure has been set by the American Conference of Governmental Hygienists (ACGIH), neither has a Workplace Exposure Limit been established for TEG. TEG is readily biodegradable, has a low potential to bioaccumulate and has low toxicity to aquatic organisms.
TEG is not flammable, unless preheated. | | Flammability and Explosibility | Notclassified | | Chemical Reactivity | Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. | | Safety Profile | Poison by intravenous
route. Mildly toxic to humans by ingestion.
Experimental reproductive effects. An eye
and skin irritant. Many glycol ether
compounds have dangerous human
reproductive effects. Combustible when
exposed to heat or flame. Can react with
oxidizing materials. Explosive in the form of
vapor when exposed to heat, flame, or
spark. To fight fire, use alcohol foam, dry
chemical. When heated to decomposition it
emits acrid smoke and irritating fumes. See
also ESTERS and GLYCOL ETHERS. | | Purification Methods | Dry the glycol with CaSO4 for 1 week, then it is repeatedly and very slowly fractionally distilled under a vacuum. Store it in a vacuum desiccator over P2O5. It is very hygroscopic. [Beilstein 1 IV 2400.] |
| | Triethylene glycol Preparation Products And Raw materials |
| Raw materials | ETHYLENE OXIDE-->Oxygen-->O1-(DIMETHOXYTRITYL)TRIETHYLENE GLYCOL | | Preparation Products | Kryptofix 222-->[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid-->DIBENZANTHRONE-->NONAETHYLENE GLYCOL MONOMETHYL ETHER-->5-(2-THIENYL)PENTANOIC ACID-->2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL-->KRYPTOFIX(R) 221-->2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL-->Benzoic acid, 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-4-nitro--->[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis--->1-(9-MERCAPTONONYL)-3,6,9-TRIOXAUNDECAN-11-OL-->1,8-Diazido-3,5-dioxaoctane-->TRIETHYLENE GLYCOL BIS(CHLOROFORMATE)-->2,5,8,11,14,17-Hexaoxanonadecan-19-ol, methanesulfonate-->HO-PEG3-CH2COOH-->TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER |
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