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| | 23-HYDROXYBETULINIC ACID Basic information |
| Product Name: | 23-HYDROXYBETULINIC ACID | | Synonyms: | ANEMOSAPOGININ;23-HYDROXYBETULINIC ACID;3β,23-Dihydroxylup-20(29)-en-28-oic acid;3beta,23-Dihydroxylup-20(29)-en-28-oic acid;Anemosapogenin,23-Hydroxybetulinic acid;(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aS,13bR)-9-hydroxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid;23-Hydroxybetulinic Acid, ≥98%;23-Hydroxybetulinic acid 85999-40-2 | | CAS: | 85999-40-2 | | MF: | C30H48O4 | | MW: | 472.7 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 85999-40-2.mol |  |
| | 23-HYDROXYBETULINIC ACID Chemical Properties |
| Melting point | >293°C (dec.) | | Boiling point | 585.8±25.0 °C(Predicted) | | density | 1.106 | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Methanol (Slightly, Heated), Pyridine (Slightly) | | form | Solid | | pka | 4.60±0.70(Predicted) | | color | White |
| | 23-HYDROXYBETULINIC ACID Usage And Synthesis |
| Description | 23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity. It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 μM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 μM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels. | | Uses | 23-Hydroxybetulinic Acid is a potential cytoxic agent in the treatment of cancer. Apoptotic effect. Antiproliferative. | | Definition | ChEBI: 23-Hydroxybetulinic acid is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane. |
| | 23-HYDROXYBETULINIC ACID Preparation Products And Raw materials |
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