Anastrozole EP Impurity I

Anastrozole EP Impurity I Basic information
Product Name:Anastrozole EP Impurity I
Synonyms:2-[3-CHLOROMETHYL-5-(CYANO-DIMETHYL-METHYL)-PHENYL]-2-METHYL-PROPIONITRILE;Anastrozole EP Impurity I;2-[3-(chloromethyl)-5-(2-cyanopropan-2-yl)phenyl]-2-methylpropanenitrile;Anastrozole Impurity 14(EP Impurity I);2,2′-[5-(Chloromethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile);1,3-Benzenediacetonitrile, 5-(chloromethyl)-α1,α1,α3,α3-tetramethyl-;2,2'-(5-(chloromethyl)-1,3-phenylene)bis(2-methylpropanenitrile);Anastrozole Impurity 14(Anastrozole EP Impurity I)
CAS:120511-91-3
MF:C15H17ClN2
MW:260.76
EINECS:
Product Categories:
Mol File:120511-91-3.mol
Anastrozole EP Impurity I Structure
Anastrozole EP Impurity I Chemical Properties
Safety Information
MSDS Information
Anastrozole EP Impurity I Usage And Synthesis
Uses5-(Chloromethyl)-α1,α1,α3,α3-tetramethyl-1,3-benzenediacetonitrile (Anastrozole EP Impurity I) is an impurity of Anastrozole (A637425), an aromatase inhibitor which functions as an antineoplastic (1,2). Anastrozole is used i post-menopausal women with advanced breast cancer.
Anastrozole EP Impurity I Preparation Products And Raw materials
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) p-Toluenesulfonic acid monohydrate 3,5-Bis(bromomethyl)toluene Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-BenzenediacetaMide) 3,5-Bis(2-cyanoprop-2-yl)toluene α-Desmethyl Anastrozole Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetaMide) 5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Anastrozole Dimer Impurity Anastrozole iMpurity Anastrozole N-glucuronide 5-Methyl-1,3-benzenediacetonitrile Anastrozole Impurity 11 Anastrozole Di-Destriazole Anastrozole DiMer IMpurity NA 3,5-Bis(2-cyanoprop-2-yl)benzyl bromide

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