FUSARENON X

FUSARENON X Basic information
Product Name:FUSARENON X
Synonyms:4-acetyloxy-12,13-epoxy-3,7,15-trihydroxy-(3-alpha,4-beta,7-beta)-trichothec-9;7-beta)--bet;-9-en-8-one;-en-8-one;Fusarenon;Fusarenone X;fusarenonex;nivalenol-4-o-acetate
CAS:23255-69-8
MF:C17H22O8
MW:354.36
EINECS:621-752-1
Product Categories:Chiral Reagents;Intermediates & Fine Chemicals;Mutagenesis Research Chemicals;Pharmaceuticals;mycotoxin
Mol File:23255-69-8.mol
FUSARENON X Structure
FUSARENON X Chemical Properties
Melting point 91-92℃
Boiling point 407.59°C (rough estimate)
density 1.2646 (rough estimate)
refractive index 1.4430 (estimate)
Fp 2 °C
storage temp. −20°C
solubility Dichloromethane: Soluble
pka11.70±0.70(Predicted)
form neat
CAS DataBase Reference23255-69-8
Safety Information
Hazard Codes F,Xn,T+
Risk Statements 11-20/21/22-36-36/37/38-28
Safety Statements 26-36/37-45-36/37/39-22-16
RIDADR 3172
WGK Germany 3
RTECS YD0160000
HazardClass 6.1(a)
PackingGroup I
HS Code 2932990090
Hazardous Substances Data23255-69-8(Hazardous Substances Data)
MSDS Information
FUSARENON X Usage And Synthesis
DescriptionFusarenon X is a type B trichothecene mycotoxin typically derived from Fusarium species. It is primarily found in contaminated cereals. Fusarenon X inhibits protein synthesis, which leads to disruption of DNA synthesis. As this occurs in actively proliferating cells, fusarenon X causes immunosuppression, intestinal malabsorption, developmental toxicity, and genotoxicity. Fusarenon X can be metabolized to fusarenon X-glucoside by infected plants.
UsesA mycotoxin produced by Fusarium, having immunosuppressive and carcinogenic properties.
Safety ProfilePoison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
FUSARENON X Preparation Products And Raw materials
(1R)-TRANS-1,2-CYCLOPENTANEDIOL MONOACETATE trans-1,2-Cyclopentanediol Ethylhexylglycerin 1,2-epoxy-2,4,4-trimethylpentane FUSARENON X 3-METHYL-2-CYCLOHEXEN-1-OL (R)-(+)-2,3-EPOXYPROPYL HEXYL ETHER 1,2-EPOXY-7-OCTENE 2-METHYL-2-CYCLOHEXEN-1-ONE (TETRAHYDRO-PYRAN-3-YL)-METHANOL Allyl glycidyl ether (1R)-TRANS-1,2-CYCLOPENTANEDIOL (R)-(-)-Methyl glycidyl ether 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL 1,3-CYCLOPENTANEDIOL (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL (S)-2-Methyl Glycidol Acetic acid 3-hydroxy-2,3-dimethyl-butyl ester

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