Abacavir Impurity F

Abacavir Impurity F Basic information
Product Name:Abacavir Impurity F
Synonyms:6-N-cyclopropyl-9-[(1R,4S)-4-[(2-methylpropan-2-yl)oxymethyl]cyclopent-2-en-1-yl]purine-2,6-diamine;Abacavir Impurity 6(Abacavir EP Impurity F);(Abacavir EP Impurity F);Abacavir impurity 3;Abacavir EP Imp F;Abacavir t-Butyl Ether;6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine;9H-Purine-2,6-diamine, N6-cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-
CAS:1443421-68-8
MF:C18H26N6O
MW:342.44
EINECS:
Product Categories:
Mol File:1443421-68-8.mol
Abacavir Impurity F Structure
Abacavir Impurity F Chemical Properties
Boiling point 580.3±60.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka4.86±0.10(Predicted)
color Pale Orange to Light Orange
Safety Information
MSDS Information
Abacavir Impurity F Usage And Synthesis
UsesN6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine (Abacavir EP Impurity F) is an impurity of Abacavir (A104990), a guanosine analog that inhibits reverse transcriptase (NRTI)?(1,2).
Abacavir Impurity F Preparation Products And Raw materials
Abacavir Related CoMpound D Abacavir (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- 2-Amino-6-cyclopropylamino-9H-purine (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol Abacavir 5’-Phosphate Abacavir Clorabacavir racemic trans-Abacavir Hydrochloride Abacavir Impurity 6 Abacavir Carboxylate Abacavir Impurity 1 Abacavir Impurity A Abacavir Abacavir 5'-Glucuronide NA Abacavir-d4

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