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| | DL-Norvaline Basic information |
| Product Name: | DL-Norvaline | | Synonyms: | NORVALINE, DL-;alpha-DL-Aminopentanoic acid;dl-alpha-Amino-N-valenic acid;DL-alpha-Aminovaleric acid;Valeric acid, 2-amino-, DL-;α-DL-aminopentanoicacid;(R,S)-2-aminopentanoic acid;DL-Norvaline≥ 99.5% (HPLC) | | CAS: | 760-78-1 | | MF: | C5H11NO2 | | MW: | 117.15 | | EINECS: | 212-082-7 | | Product Categories: | Norvaline [Nva];Peptide | | Mol File: | 760-78-1.mol |  |
| | DL-Norvaline Chemical Properties |
| Melting point | ≥300 °C (dec.) | | Boiling point | 222.9±23.0 °C(Predicted) | | density | 1.2000 (estimate) | | refractive index | 1.4650 (estimate) | | storage temp. | Store below +30°C. | | solubility | 83.9g/l | | pka | 2.36, 9.72(at 25℃) | | form | Solid | | color | White to Off-White | | optical activity | [α]25/D 0.00±0.10°, c = 2 in 5 M HCl | | Water Solubility | 1 g/10 mL (18 ºC) | | Merck | 14,6716 | | BRN | 1721163 | | InChIKey | SNDPXSYFESPGGJ-UHFFFAOYSA-N | | CAS DataBase Reference | 760-78-1(CAS DataBase Reference) | | NIST Chemistry Reference | (Dl) 2-aminopentanoic acid(760-78-1) | | EPA Substance Registry System | Norvaline (760-78-1) |
| | DL-Norvaline Usage And Synthesis |
| Chemical Properties | white to off-white crystals or crystalline powder | | Uses | DL-Norvaline is a neurotransmitter. | | Uses | DL-Norvaline has been used as an internal standard:
- to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
- to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
- for free amino acid analysis in samples of oocytes by liquid chromatography
| | Definition | ChEBI: An alpha-amino acid that is valeric acid which is substituted at position 2 by an amino group. | | General Description | DL-Norvaline, a non-protein amino acid, is of significance in metabolic pathways. It is used as a food additive on account of its nutritional and functional characteristics that are beneficial to health. | | Biochem/physiol Actions | Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins. |
| | DL-Norvaline Preparation Products And Raw materials |
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