3,3'-Dimethoxybenzidine dihydrochloride

3,3'-Dimethoxybenzidine dihydrochloride Basic information
Product Name:3,3'-Dimethoxybenzidine dihydrochloride
Synonyms:3,3’-dimethoxy-4,4’-diaminobiphenyldihydrochloride;3,3’-dimethoxy-benzidindihydrochloride;3,3-dimethoxybiphenyl-4,4-ylenediammonium dichloride;ortho-dianisidine dihydrochloride;O-DIANISIDINE DIHYDROCHLORIDE 10 MG*TABL ETS, TRU-ME;3,3'-DIMETHOXYBENZIDINE HYDROCHLORIDE HY DRATE;3,3'-DIMETHOXYBENZIDINE DIHYDROCHLORIDE, PGE WITH 50 TABL.;2-Dianisidinedi2HCl
CAS:20325-40-0
MF:C14H17ClN2O2
MW:280.75
EINECS:243-737-5
Product Categories:Biphenyl & Diphenyl ether
Mol File:20325-40-0.mol
3,3'-Dimethoxybenzidine dihydrochloride Structure
3,3'-Dimethoxybenzidine dihydrochloride Chemical Properties
Melting point 268 °C
Fp 206℃
storage temp. 2-8°C
solubility H2O: soluble25mg/mL
form tablet
color Light beige to purple-gray
PH1.7 at 20℃ and 100g/L
Water Solubility 1-5 g/100 mL at 20 ºC
BRN 3917996
InChIKeyUXTIAFYTYOEQHV-UHFFFAOYSA-N
CAS DataBase Reference20325-40-0(CAS DataBase Reference)
EPA Substance Registry System3,3'-Dimethoxybenzidine dihydrochloride (20325-40-0)
Safety Information
Hazard Codes T
Risk Statements 45-22
Safety Statements 53-45
RIDADR 2811
WGK Germany 3
RTECS DD1050000
TSCA Yes
HazardClass 6.1(a)
PackingGroup II
HS Code 29222990
MSDS Information
3,3'-Dimethoxybenzidine dihydrochloride Usage And Synthesis
Descriptiono-Dianisidine (dihydrochloride) is a colorimetric peroxidase substrate that has been used as a substrate to semi-quantitatively measure lactate, uric acid , and glucose. It has also been used as a reagent for the detection of various metals, thiocyanates, and nitrites. This aromatic amine is initially colorless but turns to violet upon oxidization and is spectrophotometrically measured at a wavelength of 405 nm.
Chemical PropertiesOff-white or grey tablets
Useso-Dianisidine (3,3′-dimethoxybenzidine) has been used as a component of GO (glucose oxidase) reagent, which is used for measuring the glucose content. It has also been used as a substrate to measure myeloperoxidase activity.
UsesIt is suitable for use in ELISA procedures. In neurohistochemistry o-Dianisidine dihydrochloride has demonstrated perikaryal labeling as well as retrograde and anterograde transport to the primary olfactory cortex. It has also been used for a paper based-micro fluidic device to semi-quantitatively measure lactate, uric acid, and glucose. 3,3'-Dimethoxybenzidine is used principally as an intermediate in the production of commercial bisazobiphenyl dyes for coloring textiles, paper, plastic, rubber, and leather.
General DescriptionOff-white powder.
Air & Water ReactionsWater soluble.
Reactivity Profile3,3'-Dimethoxybenzidine dihydrochloride is an ether substituted acidic organic salt. Reacts weakly as a acid to neutralize bases. May react with strong oxidizing agents or strong reducing agents.
Fire HazardFlash point data are not available for 3,3'-Dimethoxybenzidine dihydrochloride, but 3,3'-Dimethoxybenzidine dihydrochloride is probably combustible.
Safety ProfileConfirmed carcinogen with experimental carcinogenic and tumorigenic data. Experimental reproductive data. Mutation data reported.When heated to decomposition it emits very toxic fumes of NO, and HCl.
3,3'-Dimethoxybenzidine dihydrochloride Preparation Products And Raw materials
Preparation ProductsNitrotetrazolium blue chloride-->disodium 3-[[4'-[(6-amino-1-hydroxy-3-sulphonato-2-naphthyl)azo]-3,3'-dimethoxy[1,1'-biphenyl]-4-yl]azo]-4-hydroxynaphthalene-1-sulphonate-->DIRECT BLUE 15
3,3'-Dimethoxybenzidine dihydrochloride 2,3-DIMETHOXYANILINE Diphenyldimethoxysilane Aniline hydrochloride Biphenyl Dimethyldimethoxysilane Benzidine dihydrochloride Benzidine 4-(4-aminomethoxyphenyl)methoxyaniline Dimethylamine hydrochloride FAST BLUE B SALT FOR MICROSCOPY Pigment Yellow 12 1,1-Dimethoxyethane Dihydrochloride o-Dianisidine HYDRAZINE O-Tolidine Dimethoxymethane

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