Scopine

Scopine Basic information
Product Name:Scopine
Synonyms:SCOPINE;(1alpha,2beta,4beta,5alpha,7beta)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02.4]nonan-7-ol;SCOPINE, 97+%;(1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7β-ol;(1β,2α,4α,5β,7α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;3-Oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol,9-Methyl-, (1a,2b,4b,5a,7b)-;Atropine Impurity 2
CAS:498-45-3
MF:C8H13NO2
MW:155.2
EINECS:102-503-4
Product Categories:API intermediates;Tiotropium Bromide Intermediates;Inhibitors;498-45-3
Mol File:498-45-3.mol
Scopine Structure
Scopine Chemical Properties
Melting point 73.0 to 77.0 °C
Boiling point 281.3±40.0 °C(Predicted)
density 1.284±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Dichloromethane; Methanol
pka14?+-.0.20(Predicted)
form Solid
color White
InChIKeyFIMXSEMBHGTNKT-RZVDLVGDSA-N
CAS DataBase Reference498-45-3(CAS DataBase Reference)
Safety Information
HS Code 29349990
MSDS Information
Scopine Usage And Synthesis
Chemical PropertiesWhite to white crystal powder
UsesScopin is an Intermediate in the synthesis of Scopine Methobromide (Tiotropium EP Impurity G) (S199985), an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.
Biological Activityscopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.
Scopine Preparation Products And Raw materials
Raw materialsScopolamine hydrobromide
METHSCOPOLAMINE BROMIDE 5-Methyl-1H-benzotriazole Scopine N-Methyl-2-pyrrolidone SCOPOLAMINE METHYL NITRATE Tolyltriazole Cimetropium bromide Tiotropium bromide APOHYOSCINE Phenethyl alcohol Scopoletin SCOPOLAMINE N-OXIDE HYDROBROMIDE N-NONANE Hyoscine hydrobromide, Scopine tropate,(-)-Scopolamine trihydrate hydrobromide, Hyoscine hydrobromide, Scopine tropate SCOPOLAMINE METHYL CHLORIDE, [N-METHYL-3H] 2,2,6,6-Tetramethyl-4-piperidinol Hexamethyldisilazane (-)-SCOPOLAMINE PERCHLORATE

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