Cbz-L-tert-Leucine

Cbz-L-tert-Leucine Basic information

Product Name:	Cbz-L-tert-Leucine
Synonyms:	2S-BenzyloxycarbonylaMino-3,3-diMethylbutyric Acid;3-Methyl-N-[(phenylMethoxy)carbonyl]-L-valine;Benzyloxycarbonyl-L-tert-leucine;N-(Benzyloxycarbonyl)-L-tert-butylglycine;N-Benzyloxycarbonyl-tert-leucine;N-Carbobenzoxy-(S)-tert-leucine;(S)-2-(((Benzyloxy)carbonyl)aMino)-3,3-diMethylbutanoic acid;(2S)-2-([(Benzyloxy)Carbonyl]AMino)-3,3-DiMethylbutanoic Acid DicyclohexylaMine Salt
CAS:	62965-10-0
MF:	C14H19NO4
MW:	265.3
EINECS:
Product Categories:	Amino Acids & Derivatives;CHIRAL CHEMICALS;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Deriv.;Amino Acid Derivatives;Leucine [Leu, L];Aromatics
Mol File:	62965-10-0.mol

Cbz-L-tert-Leucine Chemical Properties

Boiling point	436.4±38.0 °C(Predicted)
density	1.160±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Oil
pka	4.01±0.10(Predicted)
color	Pale to Light Yellow
CAS DataBase Reference	62965-10-0

Safety Information

HazardClass	IRRITANT
HS Code	29225090

MSDS Information

Cbz-L-tert-Leucine Usage And Synthesis

Chemical Properties	Pale Yellow Thick Oil
Uses	Cbz-L-tert-Leucine is a leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors.

Cbz-L-tert-Leucine Preparation Products And Raw materials

Raw materials	N-[(Benzyloxy)carbonyl]-3-methylvaline-->BENZYL 4-NITROPHENYL CARBONATE-->Z-TLE-OH DCHA-->Benzyl carbamate-->N-(Benzyloxycarbonyloxy)succinimide-->Benzyl chloroformate-->L-tert-Leucine-->Benzyl alcohol
Preparation Products	methyl (2S)-2-amino-3,3-dimethylbutanoate

CBZ-L-VALINOL Cbz-L-tert-Leucine (-)-N-FORMYL-L-TERT-LEUCINE N-CARBOBENZOXY-DL-VALINE N,N-Dimethylformamide (S)-CBZ-1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID N-Carbobenzyloxyglycine CBZ-L-TERT-LEUCINE DICYCLOHEXYLAMMONIUM SALT Cbz-D-tert-leucine L-VALINE, 3-METHYL-N-[(PHENYLMETHOXY)CARBONYL]-, METHYL ESTER N-Carbobenzyloxy-L-valine Methoxycarbonyl-L-tert-leucine Dimethyl fumarate DL-tert-Leucine Dimethyl sulfoxide N-CARBOBENZOXY-DL-LEUCINE L-tert-Leucine Dimethyl sulfate

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