ChemicalBook Product Catalog Organic Chemistry Alcohols,Phenols,Phenol alcohols α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol

α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol

α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol Basic information
Product Name:α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
Synonyms:α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol;1H-Imidazo[4,5-c]quinoline-1-ethanol, 2-(ethoxymethyl)-α,α-dimethyl-
CAS:144875-99-0
MF:C17H21N3O2
MW:299.37
EINECS:
Product Categories:
Mol File:144875-99-0.mol
α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol Structure
α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol Chemical Properties
Boiling point 506.0±40.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
pka14?+-.0.29(Predicted)
form Solid Brown
color Light
Safety Information
MSDS Information
α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol Usage And Synthesis
Uses2-(Ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5 is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol Preparation Products And Raw materials
Raw materialsN-(4-chloroquinolin-3-yl)-2-ethoxyacetamide-->1-[(3-amino-4-quinolinyl)amino]-2-methyl-2-propanol-->1-Amino-2-methylpropan-2-ol-->Ethoxyacetic acid
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