Febuxostat Descyano Impurity

Febuxostat Descyano Impurity Basic information
Product Name:Febuxostat Descyano Impurity
Synonyms:3-Descyano Febuxostat;Febuxostat Descyano Impurity;2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat-5;Febuxostat Impurity 13/Febuxostat Descyano Impurity/2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat Impurity IV;2-(4-isobutoxyphenyl)-4-methylthiazole;5-Thiazolecarboxylic acid, 4-methyl-2-[4-(2-methylpropoxy)phenyl]-
CAS:1206550-99-3
MF:C15H17NO3S
MW:291.37
EINECS:
Product Categories:ZY
Mol File:1206550-99-3.mol
Febuxostat Descyano Impurity Structure
Febuxostat Descyano Impurity Chemical Properties
Melting point 192-194°C
Boiling point 471.5±55.0 °C(Predicted)
density 1.213±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka1.30±0.37(Predicted)
form Solid
color Off-White to Pale Beige
Stability:Hygroscopic
Safety Information
MSDS Information
Febuxostat Descyano Impurity Usage And Synthesis
Uses3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
Febuxostat Descyano Impurity Preparation Products And Raw materials
isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate FeBuxostat Impurity 26 FeBuxostat Impurity 33 Febuxostat impurity 37 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 18 ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Febuxostat Impurity 14 Febuxostat Bromo Impurity 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid FeBuxostat Impurity 32 ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid

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