ChemicalBook Product Catalog Chemical Reagents Organic reagents Aromatics 2-Amino-4-chlorobenzoic acid

2-Amino-4-chlorobenzoic acid

2-Amino-4-chlorobenzoic acid Basic information
Product Name:2-Amino-4-chlorobenzoic acid
Synonyms:4-CHLORO-2-AMINOBENZOIC ACID;2,4-ACBA;3-AMINO-4-CARBOXY-1-CHLOROBENZENE;2-AMINO-4-CHLOROBENZOIC ACID;2-CARBOXY-5-CHLOROANILINE;4-chloroanthranil acid;p-Chloro-o-Amino Benzoic Acid;4-ChloroanthranilicAcid98%
CAS:89-77-0
MF:C7H6ClNO2
MW:171.58
EINECS:201-938-5
Product Categories:API Intermediate;FINE Chemical & INTERMEDIATES;Amines;blocks;Carboxes;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid series;API;bc0001;89-77-0
Mol File:89-77-0.mol
2-Amino-4-chlorobenzoic acid Structure
2-Amino-4-chlorobenzoic acid Chemical Properties
Melting point 231-233 °C (lit.)
Boiling point 250°C (rough estimate)
density 1.3246 (rough estimate)
refractive index 1.5560 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility almost transparency in 1mol/L NaOH
form Powder
pka4.71±0.10(Predicted)
color Beige to light brown
Water Solubility slightly soluble
BRN 743349
InChIKeyJYYLQSCZISREGY-UHFFFAOYSA-N
CAS DataBase Reference89-77-0(CAS DataBase Reference)
NIST Chemistry Reference2-Amino-4-chlorobenzoic acid(89-77-0)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-36-37/39
WGK Germany 3
RTECS DG1570000
HS Code 29163990
MSDS Information
ProviderLanguage
4-Chloroanthranilic acid English
SigmaAldrich English
ACROS English
ALFA English
2-Amino-4-chlorobenzoic acid Usage And Synthesis
Chemical Propertiesoff-white powder
Uses2-Amino-4-chlorobenzoic Acid is used in the preparation of quinazolinone derivatives observed to be useful in the treatment of Alzheimer’s disease. Also it aids in the synthesis of non-nucleoside, thumb pocket 2 HCV NS5B polymerase inhibitors used in Hepatitis C therapy.
DefinitionChEBI: 2-Amino-4-chlorobenzoic acid is an aminobenzoic acid.
2-Amino-4-chlorobenzoic acid Preparation Products And Raw materials
Preparation Products3',4'-DICHLOROACETOPHENONE-->1-Acetyl-5-broMo-6-chloro-1H-indol-3-yl acetate-->USP7-IN-1-->N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine-->4,7-Dichloroquinazoline-->7-CHLORO-4-QUINAZOLINOL-->6-Amino-11-chloronaphth[2,3-c]acridine-5,8,14(13H)-trione-->7-Chloro-3-hydroxybenzo[d][1,2,3]triazin-4(3H)-one-->7-chloro-3-(2-methylphenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one-->2-Chloro-9,10-dihydro-9,10-[1,2]benzenoanthracene-->5-Bromo-4-chloro-2-iodo-benzoic acid-->7-Chloro-2-(trifluoromethyl)quinazolin-4(1H)-one-->3-AMINO-7-CHLORO-2-METHYLQUINAZOLIN-4(3H)-ONE-->7-Chloro-2-chloroMethyl-1H-quinazolin-4-one
2-AMINO-5-CHLOROBENZOIC ACID Methyl anthranilate 2-Amino-4-chlorobenzoic acid 6-CHLOROISATIN 7-CHLORO-2-PHENYL-3,1-BENZOXAZIN-4-ONE POLYURETHANE 3-AMINO-4-CHLOROBENZOIC ACID 2-(P-AMYLCINNAMOYL)AMINO-4-CHLOROBENZOIC ACID 4-Aminobenzoic acid Urethane Glycine 4-Chlorobenzoic acid 2-Amino-4-chlorophenol 2-Chlorobenzoic acid 7-CHLORO-2-[2-(CHLOROMETHYL)PHENYL]-4H-3,1-BENZOXAZIN-4-ONE 2-AMINO-4-CHLOROBENZOIC ACID 4-CHLORO-2-(4-METHOXY-PHENYLAMINO)-BENZOIC ACID Anthranilic acid
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