ChemicalBook Product Catalog Biochemical Engineering Polypeptide AC-DEVD-AMC

AC-DEVD-AMC

AC-DEVD-AMC Basic information
Product Name:AC-DEVD-AMC
Synonyms:AC-ASP-MET-GLN-ASP-AMC;AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN;AC-ASP-GLU-VAL-ASP-MCA;AC-ASP-GLU-VAL-ASP-7-AMINO-4-METHYLCOUMARIN;AC-ASP-GLU-VAL-ASP-AMC;AC-ASP-GLU-VAL-ASP-AMC AMMONIUM SALT;AC-DEVD-AMC;AC-DEVD-AMC AMMONIUM SALT
CAS:169332-61-0
MF:C30H37N5O13
MW:675.64
EINECS:
Product Categories:Pepetides;peptide
Mol File:169332-61-0.mol
AC-DEVD-AMC Structure
AC-DEVD-AMC Chemical Properties
Boiling point 1200.1±65.0 °C(Predicted)
density 1.423±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: 10 mM
form powder
pka4.09±0.10(Predicted)
color white
InChIKeyALZSTTDFHZHSCA-RNVDEAKXSA-N
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
AC-DEVD-AMC Usage And Synthesis
UsesN-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.
Biochem/physiol ActionsFluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
AC-DEVD-AMC Preparation Products And Raw materials
4-Methylcumarin AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN AC-DEVD-AMC N-acetyl aspartyl-glutaMic acid 4-(3-METHOXYANILINO)-4-OXOBUTANOIC ACID CASPASE-3 SUBSTRATE AC-DEVD-AMC TFA CHEMBRDG-BB 5539774 AC-DEVD-CHO AC-DEVD-AFC 4-(3-METHOXY-PHENYLAMINO)-BUTAN-1-OL SUC-ALA-ALA-ALA-AMC
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