Ginsenoside Rd

Ginsenoside Rd Basic information
Product Name:Ginsenoside Rd
Synonyms:2-o-beta-d-glucopyranosyl-(3beta,12beta)-20-(beta-d-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-d-glucopyranoside;GINSENOSIDE RD;beta-d-glucopyranoside,(3-beta,12-beta)-20-(beta-d-glucopyranosyloxy)-12-hydro;(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside;Ginsenoside Rd 52705-93-8;b-D-Glucopyranoside, (3b,12b)-20-(b-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-b-D-glucopyranosyl-;xydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-;GINSENOOSIDERD
CAS:52705-93-8
MF:C48H82O18
MW:947.15
EINECS:258-118-5
Product Categories:Inhibitors;reference standards from Chinese medicinal herbs (TCM).;Ginsenoside series;chemical reagent;pharmaceutical intermediate;standardized herbal extract;Saponins;The group of Ginsenosides;phytochemical
Mol File:52705-93-8.mol
Ginsenoside Rd Structure
Ginsenoside Rd Chemical Properties
Melting point 204~206℃
Boiling point 1015.6±65.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka12.85±0.70(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
LogP3.110 (est)
CAS DataBase Reference52705-93-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 2-45
WGK Germany 3
HS Code 29389090
MSDS Information
Ginsenoside Rd Usage And Synthesis
DescriptionGinsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities.
Chemical PropertiesWhite to off-white crystals powder
UsesGinsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.
DefinitionChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3.
Ginsenoside Rd Preparation Products And Raw materials
Ginsenoside Rh1 Ginsenoside Rh2 GINSENOSIDEF1 Ginsenoside Re Ginsenoside Rb1 Ginsenoside Rg1 Ginsenoside CK Ginsenoside Rd SOY ASAPONIN GINSENOSIDE RE TRIBULOSIDE 20(R)-Ginsenoside Rg3 3,3,5,5-TETRAMETHYLCYCLOHEXANOL Ginseng extract Cyclohexane,3-(ethoxymethoxy)-1,1,5-trimethyl- 2-[2-[(2-ETHYLHEXYL)OXY]ETHOXY]ETHANOL Menthoxypropanediol PROTOPANAXTRIOL

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