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| Ginsenoside Rd Basic information |
| Ginsenoside Rd Chemical Properties |
Melting point | 204~206℃ | Boiling point | 1015.6±65.0 °C(Predicted) | density | 1.38±0.1 g/cm3(Predicted) | storage temp. | Inert atmosphere,2-8°C | solubility | DMSO (Slightly), Methanol (Slightly) | pka | 12.85±0.70(Predicted) | form | Solid | color | White to Off-White | Stability: | Hygroscopic | LogP | 3.110 (est) | CAS DataBase Reference | 52705-93-8(CAS DataBase Reference) |
Hazard Codes | Xn | Risk Statements | 22 | Safety Statements | 2-45 | WGK Germany | 3 | HS Code | 29389090 |
| Ginsenoside Rd Usage And Synthesis |
Description | Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities. | Chemical Properties | White to off-white crystals powder | Uses | Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia. | Definition | ChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3. |
| Ginsenoside Rd Preparation Products And Raw materials |
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