ChemicalBook Product Catalog Natural Products Iridoid derivatives IVHD-valtrate

IVHD-valtrate

IVHD-valtrate Basic information
Product Name:IVHD-valtrate
Synonyms:IVHD-valtrate;Isovaleroxyhydroxydidrovaltratum;Isovaleroxyhydroxydihydrovaltrate;Valtrate HD;Butanoic acid, 3-methyl-2-(3-methyl-1-oxobutoxy)-, [(1S,2'R,4aR,6S,7aS)-6-(acetyloxy)-4a,5,6,7a-tetrahydro-4a-hydroxy-1-(3-methyl-1-oxobutoxy)spiro[cyclopenta[c]pyran-7(1H),2'-oxiran]-4-yl]methyl ester
CAS:28325-56-6
MF:C27H40O11
MW:540.6
EINECS:
Product Categories:
Mol File:28325-56-6.mol
IVHD-valtrate Structure
IVHD-valtrate Chemical Properties
Safety Information
MSDS Information
IVHD-valtrate Usage And Synthesis
Biological ActivityIVHD-valtrate is an active Valeriana jatamansi derivative that inhibits human ovarian cancer cells in vitro and in vivo. It induces apoptosis of cancer cells and inhibits ovarian cancer cells from arresting in G2/M phase. It has the potential to be a new chemotherapeutic agent for human ovarian cancer research.
in vitro

IVHD-valtrate inhibits the growth and proliferation of the A2780 and OVCAR-3 ovarian cancer cell lines in a concentration-dependent manner. IVHD-valtrate results in a relatively low cytotoxicity to immortalized non-tumorigenic human ovarian surface epithelial cells (IOSE-144).

target

IC50: apoptosis

IVHD-valtrate Preparation Products And Raw materials
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Hydroxyecdysone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol hydroxygenkwanin alpha-Terpineol beta-Eudesmol MOSLOFLAVONE alpha-Cyperone
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