Loratadine EP IMpurity F

Loratadine EP IMpurity F Basic information
Product Name:Loratadine EP IMpurity F
Synonyms:Loratadine EP IMpurity F;1-Piperidinecarboxylic acid, 4-( 8-chloro-11-fluoro-6,11-dihydro -5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester;Loratadine Impurity 4/Loratadine EP Impurity F;OVPFJWGOZPZTKG-UHFFFAOYSA-N;Loratadine Impurity 6(Loratadine EP Impurity F);Ethyl 4-[(11RS)-8-Chloro-11-fluoro-;Ethyl 4-((11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidi;ethyl 4-(8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate
CAS:125743-80-8
MF:C22H24ClFN2O2
MW:402.89
EINECS:
Product Categories:
Mol File:125743-80-8.mol
Loratadine EP IMpurity F Structure
Loratadine EP IMpurity F Chemical Properties
Melting point 149-153 °C
Boiling point 490.3±45.0 °C(Predicted)
density 1.29±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form neat
pka3.65±0.40(Predicted)
Safety Information
MSDS Information
Loratadine EP IMpurity F Usage And Synthesis
UsesLoratadine Impurity F (Loratadine EP Impurity F; Loratadine USP Related Compound G Impurity) is a fluorinated analog of Loratadine (L469575), which is a nonsedating-type histamine H1-receptor.
Loratadine EP IMpurity F Preparation Products And Raw materials
3-Hydroxy loratadine Loratadine EP IMpurity A 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Loratadine Impurity 8 (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one (Loratadine Impurity) 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Loratadine Impurity 16 Loratadine EP Impurity E Loratadine Side Chain Impurity 8-Dechloro-7-chloro Loratadine 4-chloro-loratadine Sch 37370 8-Dechloro-10-chloro Loratadine Desloratadine N-Hydroxypiperidine Desloratadine Impurity Loratadine Impurity 12

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