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Montelukast Impurity H

Montelukast Impurity H Basic information
Product Name:Montelukast Impurity H
Synonyms:(R)-2-[1-[[[1-[3-[(E)-2-(7-Ch;2-[(3R)-3-[[[1-(CarboxyMethyl)cyclopropyl]Methyl]thio]-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]benzoic Acid 1-Methyl Ester;2'-Des(1-hydroxy-1-Methylethyl)-2'-Methycarboxy Montelukast;Montelukast IMpurity H;Montelukast Sodium EP impurity H;Montelukast Impurity 8(EP Impurity H);Benzoic acid, 2-[(3R)-3-[[[ 1- (carboxyMethyl)cyclopropyl] Methyl]thio]-3-[3-[(1E)-2-(7- chloro-2-quinolinyl)ethenyl] phenyl]propyl]-, 1-Methyl ester;Montelukast EP Impurity H
CAS:851755-56-1
MF:C34H32ClNO4S
MW:586.14
EINECS:
Product Categories:Aromatics;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:851755-56-1.mol
Montelukast Impurity H Structure
Montelukast Impurity H Chemical Properties
Melting point 55-56°C (dec.)
Boiling point 757.0±60.0 °C(Predicted)
density 1.299±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.76±0.10(Predicted)
form Solid
color Yellow
Safety Information
MSDS Information
Montelukast Impurity H Usage And Synthesis
Chemical PropertiesYellow Solid
Uses2’-Des(1-hydroxy-1-methylethyl)-2’-methycarboxy Montelukast (Montelukast EP Impurity H) is an impurity of the selective leukotriene D4-receptor antagonist, Montelukast (M568000).
Montelukast Impurity H Preparation Products And Raw materials
[R-(E)]-alpha-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol Montelukast Styrene Dihydro Montelukast Sodium Salt Montelukast Bis-sulfide (Mixture of Diastereomers) L 768232 Montelukast EP IMpurity E 1-(Hydroxymethyl)cyclopropaneacetonitrile Thiomethyl Cyclopropyl Acetonitrile 1,1-dimethyl-2-benzoxepin-3-yl)phenyl]ethenyl]- Montelukast Cyclopropaneacetonitrile 1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate cis-Montelukast 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol Montelukast Methyl Ketone Montelukast Michael Adduct R,S-IsoMer Montelukast (3S)-Chloro Alcohol Impurity Montelukast sodium Montelukast Sulfoxide (Mixture of diastereomers)
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