ChemicalBook Product Catalog Biochemical Engineering Inhibitors Nuclear transcription factor (NF-κB) NOD1 Inhibitor Nodinitib-1

Nodinitib-1

Nodinitib-1 Basic information
Product Name:Nodinitib-1
Synonyms:Nodinitib-1;1H-BenziMidazol-2-aMine, 1-[(4-Methylphenyl)sulfonyl]-;ML 130;1-[(4-Methylphenyl)sulfonyl]-1H-benziMidazol-2-aMine;Noditinib-1;ML130 (Nodinitib-1);CID-1088438;1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-ylamine
CAS:799264-47-4
MF:C14H13N3O2S
MW:287.34
EINECS:
Product Categories:API;NF-kB;Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:799264-47-4.mol
Nodinitib-1 Structure
Nodinitib-1 Chemical Properties
Melting point 191-192 °C (decomp)
Boiling point 532.5±43.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO: >10mg/mL
pka2.55±0.10(Predicted)
form powder
color white to beige
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
MSDS Information
Nodinitib-1 Usage And Synthesis
UsesNoditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.
DefinitionChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide.
Nodinitib-1 Preparation Products And Raw materials
Barasertib (AZD1152-HQPA) Olaparib ML-327 Veliparib 9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl- VU0456810 Trametinib Paclitaxel ML-228 AG 1478 HYDROCHLORIDE M348 1-(4-(4-(benzo[d][1,3]dioxole-5-carbonyl)piperazin-1-yl)phenyl)ethan-1-one ML 141 ML 339
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