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Desethyl Sildenafil

Desethyl Sildenafil Basic information
Product Name:Desethyl Sildenafil
Synonyms:Desethyl Sildenafil;5-[2-Hydroxy-5-(4-Methylpiperazinylsulphonyl)phenyl]1-Methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyraMidin-7-one;5-[2-Hydroxy-5-[[4-(Methyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one;Sildenafil EP IMpurity C;5-[2-Hydroxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one;O-Desethyl sildenafil;Sildenafil impurity C;Sildenafil Impurity 3(Sildenafil EP Impurity C)
CAS:139755-91-2
MF:C20H26N6O4S
MW:446.52
EINECS:200-659-6
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:139755-91-2.mol
Desethyl Sildenafil Structure
Desethyl Sildenafil Chemical Properties
Melting point >267°C (dec.)
density 1.49±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka7.02±0.50(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
Desethyl Sildenafil Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesDesethyl Sildenafil (Sildenafil EP Impurity C) is a metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
Desethyl Sildenafil Preparation Products And Raw materials
Pyrazole N-Demethyl Sildenafil 1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 5-[2-Ethoxy-5-[(4-Methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-(2-Methylpropyl)-7H-pyrazolo[4,3-d]pyriMidin-7-one 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-5-(2-hydroxyphenyl)-1-methyl-3-propyl- SILDENAFIL N-OXIDE Sildenafil DiMer IMpurity Sildenafil impurity 4-Amino-2-methyl-5-propyl-2H-pyrazole-3-carboxylic acid Homo Sildenafil DESMETHYL SILDENAFIL 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-(5-chloro-2-ethoxyphenyl)-1,6-dihydro-1-methyl-3-propyl- Propoxyphenyl Sildenafil Sildenafil EP IMpurity D 4-AMINO-1-METHYL-5-PROPYL-1H-PYRAZOLE-3-CARBOXYLIC ACID AMIDE 4-Amino-1-methyl-3-propyl-5-pyrazolecarboxamide 2-ETHOXYBENZOIC ANHYDRIDE
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