trans-Itraconazole

trans-Itraconazole Basic information
Product Name:trans-Itraconazole
Synonyms:4-[4-[4-[4-[[trans-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(1RS)-1-methylpropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one;4-(4-(4-(4-(((2S,4S)-2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one;Itraconazole Impurity 5(Itraconazole EP Impurity E);trans-Itraconazole;Itraconazole iMpurity E;3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, rel-;Itraconazole EP Impurity E (trans-Itraconazole);rel-4-(4-(4-(4-(((2S,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one (Itraconazole Impurity)
CAS:252964-65-1
MF:C35H38Cl2N8O4
MW:705.63
EINECS:
Product Categories:Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:252964-65-1.mol
trans-Itraconazole Structure
trans-Itraconazole Chemical Properties
Melting point 126 - 128°C
Boiling point 850.0±75.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly)
form Solid
pka6.47±0.40(Predicted)
color White to Off-White
Safety Information
MSDS Information
trans-Itraconazole Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
Usestrans-Itraconazole (Itraconazole EP Impurity E) is a geometrical isomer of Itraconazole (I937500). It is a COVID19-related research product.
trans-Itraconazole Preparation Products And Raw materials
Itraconazole Impurity 32 Itraconazole Impurity 34 Butyl Itraconazole 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine Itraconazole Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Propyl Itraconazole 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one (1,2,4-Triazol-4-yl) Itraconazole cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate Itraconazole Impurity 15 cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Isopropyl Itraconazole DPUDRFOQNBKHMF-YZNIXAGQSA-N 1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE

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