ChemicalBook Product Catalog Organic Chemistry Amides Sulfonic acids amino compound SACLOFEN

SACLOFEN

SACLOFEN Basic information
Product Name:SACLOFEN
Synonyms:SACLOFEN;(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID;SACLOFEN SELECTIVE GABA(B) REC;BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID;BETA-(AMINOMETHYL)-4-CHLORO-BENZENEETHANESULPHONIC ACID;3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID;β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid;3-AMino-2-(4-chlorophenyl)propane-1-sulfonic acid
CAS:125464-42-8
MF:C9H12ClNO3S
MW:249.71
EINECS:
Product Categories:GABA/Glycine receptor;GABA
Mol File:125464-42-8.mol
SACLOFEN Structure
SACLOFEN Chemical Properties
Melting point 310-315℃ (decomposition)
density 1.437±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility 0.1 M NaOH: 20 mg/mL
form solid
pka1.15±0.50(Predicted)
color white
Water Solubility Soluble in water (10mM)
InChIKeyJYLNVJYYQQXNEK-UHFFFAOYSA-N
CAS DataBase Reference125464-42-8(CAS DataBase Reference)
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
SACLOFEN Usage And Synthesis
UsesSaclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons
UsesSaclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.
DefinitionChEBI: 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid is an organochlorine compound.
Biological ActivitySelective antagonist at GABA B receptors.
Biochem/physiol ActionsSaclofen might possess sympathetic nervous system-dependent anti-inflammatory action.
storageRoom temperature
SACLOFEN Preparation Products And Raw materials
2-HYDROXYSACLOFEN SACLOFEN HYDROCHLORIDE (R)-Saclofen SACLOFEN SACLOFEN((RS)-3-AMINO-2-(4-CHLOROPHENY
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