ChemicalBook Product Catalog Biochemical Engineering Polypeptide CHARYBDOTOXIN

CHARYBDOTOXIN

CHARYBDOTOXIN Basic information
Product Name:CHARYBDOTOXIN
Synonyms:CHARYBDOTOXIN;CHARYBDOTOXIN, RECOMBINANT;CHARYBDOTOXIN, RECOMBINANT, E COLI;CHARYBDOTOXIN, LEIURUS QUINQUESTRIATUS HEBRAEUS;CHTX;PYR-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS;PYR-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (DISULFIDE BRIDGE: 7-28,13-33 AND 17-35);PYR-PHE-THR-ASN-VAL-SER-CYS-THR-THR-SER-LYS-GLN-CYS-TRP-SER-VAL-CYS-GLN-ARG-LEU-HIS-ASN-THR-SER-ARG-GLY-LYS-CYS-MET-ASN-LYS-LYS-CYS-ARG-CYS-TYR-SER-OH
CAS:95751-30-7
MF:C176H277N57O55S7
MW:4295.89
EINECS:
Product Categories:Potassium channel;Ion Channels;peptide;Potassium Channel ModulatorsCell Signaling and Neuroscience;Potassium Channel ModulatorsPeptides for Cell Biology;Ion Channel Modulating Peptides;Monovalent Ion Channels;Scorpion;Toxins and Venoms;Voltage-gated Ion Channels
Mol File:Mol File
CHARYBDOTOXIN Structure
CHARYBDOTOXIN Chemical Properties
RTECS FL7535000
storage temp. -20°C
form lyophilized powder
Water Solubility Soluble to 1 mg/ml in water
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
CHARYBDOTOXIN Usage And Synthesis
UsesBiochemical probe.
UsesCharybdotoxin has been used:
  • in the inhibition of endothelium-derived hyperpolarizing factor responses
  • in electrophysiological studies, as calcium channel blockers
  • as a transport inhibitor

Biochem/physiol ActionsPotent and selective inhibitor of the Ca2+-activated K+ channel present in GH3 anterior pituitary cells and primary bovine aortic smooth muscle cells.
storage-20°C (desiccate)
CHARYBDOTOXIN Preparation Products And Raw materials
Charybdotoxin, Recomb. CHARYBDOTOXIN, [125I]-,CHARYBDOTOXIN, [3-(125I)-TYR] [GLN12]-CHARYBDOTOXIN [HIS19]-CHARYBDOTOXIN Kv1.3, Kcna3 [Charybdotoxin-Sensitive Voltage-Dependent K+ Channel, HLK3], 471-523aa, Rabbit anti-Human, Mouse, Rat, WB/IH Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) CHARYBDOTOXIN (NATIVE) 2,4-PENTANEDIONE, SILVER DERIVATIVE Kv1.3 (extracellular) (Kcna3, Charybdotoxin-sensitive Voltage-dependent Potassium Channel, HLK3) (FITC) Kv1.3 (Kcna3, Charybdotoxin-sensitive Voltage-dependent Potassium Channel, HLK3) (GLU32)-CHARYBDOTOXIN CHARYBDOTOXIN(SYNTHETIC) COBALT(II) ACETYLACETONATE Cupric acetylacetonate charybdotoxin receptor Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE
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