ANAGRELIDE IMPURITY 5

ANAGRELIDE IMPURITY 5 Basic information
Product Name:ANAGRELIDE IMPURITY 5
Synonyms:5,6-Dichloro-1,4-dihydro-2-quinazolinamine;2-AMino-5,6-dichloro-3,4-dihydroquinazoline;ANAGRELIDE IMPURITY 5;Anagrelide Impurity 24;2-Quinazolinamine, 5,6-dichloro-1,4-dihydro-;5,6-dichloro-3,4-dihydroquinazolin-2-amine;Anagrelide Impurity 27;AgrelideImpurity3-13C6
CAS:444904-63-6
MF:C8H7Cl2N3
MW:216.07
EINECS:
Product Categories:
Mol File:444904-63-6.mol
ANAGRELIDE IMPURITY 5 Structure
ANAGRELIDE IMPURITY 5 Chemical Properties
Melting point 205 - 208oC
Boiling point 357.5±52.0 °C(Predicted)
density 1.67±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka8.41±0.20(Predicted)
form Solid
color Light Yellow to Yellow
Safety Information
MSDS Information
ANAGRELIDE IMPURITY 5 Usage And Synthesis
Uses2-Amino-5,6-dichloro-3,4-dihydroquinazoline is a metabolite of Anagrelide (A637300), a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic.
DefinitionChEBI: 2-Amino-5,6-dichloro-3,4,-dihydroquinazoline is a member of quinazolines.
ANAGRELIDE IMPURITY 5 Preparation Products And Raw materials
Anagrelide Impurity 4 Anagrelide 6,7-dichloro-3-hydroxy-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one 3-Hydroxy Anagrelide-13C-d2 Anagrelide impurity 4 Anagrelide Impurity 5 HCl Ethyl N-(2.3-dichloro-6-nitrobenzyl)glycine Ethyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate hydrobromide Anagrelide-13C3 Ethyl-2-(6-aMino-2,3-dichlorobenzylaMino)acetate Hydrochloride Anagrelide Impurity 2 HCl 3-HYDROXYANAGRELIDE Anagrelide Impurity 3-13C6

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