6-Demethoxylnobiletin

6-Demethoxylnobiletin Basic information
Product Name:6-Demethoxylnobiletin
Synonyms:6-Demethoxynobiletin;3',4' ,5,7,8-pentaMethoxyflavone;2-(3,4-Dimethoxyphenyl)-5,7,8-trimethoxy-4H-1-benzopyran-4-one;6-Demethoxylnobiletin;Isosinensetin;2-(3,4-Dimethoxyphenyl)-5,7,8-trimethoxy-4H-chromen-4-one;Isosinensetin3',4' ,5,7,8-pentamethoxyflavone;3',4',5,7,8-pentamethoxyflavon
CAS:17290-70-9
MF:C20H20O7
MW:372.37
EINECS:
Product Categories:
Mol File:17290-70-9.mol
6-Demethoxylnobiletin Structure
6-Demethoxylnobiletin Chemical Properties
Melting point 198-199℃
Boiling point 565.3±50.0 °C(Predicted)
density 1.244±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
form A solid
Safety Information
MSDS Information
6-Demethoxylnobiletin Usage And Synthesis
Chemical PropertiesYellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from orange peel.
DefinitionChEBI: Isosinensetin is an ether and a member of flavonoids.
Biological Activity6-Demethoxylnobiletin, a methoxyflavonoid extracted from green peel, has inhibitory effect on p-glycoprotein (P-gp) in MDR1-MDCKII cells.
target

P-glycoprotein

6-Demethoxylnobiletin Preparation Products And Raw materials
5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone NARIRUTIN cis-4-hydroxy-alpha,alpha,4-trimethylcyclohexanemethanol Quercetagetin 3,5,6,7,3',4'-hexamethyl ether 3,3',4',5,6,7,8-heptamethoxyflavone Naringenin Naringin dihydrochalcone NARINGENIN CHALCONE PONCIRIN FLAVONE Naringin isoxsuprine

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