|
| | (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester Basic information |
| Product Name: | (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester | | Synonyms: | (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester;Picraline;2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 14-[(acetyloxy)methyl]-3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2S,3E,6S,7aS,12aR,12bS,14R)- | | CAS: | 2671-32-1 | | MF: | C23H26N2O5 | | MW: | 410.46 | | EINECS: | | | Product Categories: | | | Mol File: | 2671-32-1.mol |  |
| | (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester Chemical Properties |
| Melting point | 160-162 °C | | Boiling point | 548.0±50.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 3.89±0.40(Predicted) |
| | (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester Usage And Synthesis |
| Description | This alkaloid which structurally resembles the Alstonia bases, is found in Picralima Klaineana and forms clusters of colourless needles from C6H6-pentane. It
has [α]25D - 124° (EtOH) and is characterized as the picrate, yellow prisms when
recrystallized from MeOH, m.p. 162-4°C. | | target | SGLT | | References | Olivieretal., Ann. Pharm., 20,361 (1962)
Olivier et al., Bull. Soc. Chim. Fr., 646 (1963)
Britten, Smith., 1. Chem. Soc., 3856 (1963)
Britten, Smith, Spiteller., Chem. & Ind., 1492 (1963) |
| | (16R)-17-(Acetoxy)-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylic acid methyl ester Preparation Products And Raw materials |
|
