Di-tert-butyl N,N-diethylphosphoramidite

Di-tert-butyl N,N-diethylphosphoramidite Basic information
Product Name:Di-tert-butyl N,N-diethylphosphoramidite
Synonyms:DI-T-BUTYL N,N-DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL N,N-DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL-N,N-DIETHYLPHOSPHOROAMIDITE;DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE, TE CH., 93%;Diethyl diethylphosphoramidite;N,N-Diethyl-phosphoraMidous Acid Bis(1,1-diMethylethyl) Ester;Phosphoramidous acid, diethyl-, bis(1,1-dimethylethyl) ester
CAS:117924-33-1
MF:C12H28NO2P
MW:249.33
EINECS:
Product Categories:Phospholipids - 13C & 2H;Regant series;Phosphorylating and Phosphitylating Agents;Organic Building Blocks;Phosphoramidites;Phosphorus Compounds;Building Blocks;Chemical Synthesis;Organic Building Blocks;Phosphorus Compounds;OLED materials,pharm chemical,electronic
Mol File:117924-33-1.mol
Di-tert-butyl N,N-diethylphosphoramidite Structure
Di-tert-butyl N,N-diethylphosphoramidite Chemical Properties
Boiling point 39-41 °C/0.3 mmHg (lit.)
density 0.896 g/mL at 25 °C (lit.)
refractive index n20/D 1.434(lit.)
Fp 173 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka4.41±0.70(Predicted)
form Oil
color Clear Colourless
Water Solubility Hydrolyzes in water. Soluble in chloroform and methanol.
Sensitive Moisture Sensitive
BRN 4175262
Stability:Moisture Sensitive
CAS DataBase Reference117924-33-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
4.4-10-21
HS Code 29319090
MSDS Information
ProviderLanguage
SigmaAldrich English
Di-tert-butyl N,N-diethylphosphoramidite Usage And Synthesis
Chemical PropertiesClear Colourless Liquid
UsesA useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.
UsesDi-tert-butyl N,N-diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters.
Di-tert-butyl N,N-diethylphosphoramidite Preparation Products And Raw materials
Di-tert-butyl N,N-diethylphosphoramidite Di-tert-butyl N,N-diisopropylphosphoramidite Diethylamine

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