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| | Prednisolone succinate Basic information |
| Product Name: | Prednisolone succinate | | Synonyms: | PREDNISOLONE 21-HEMISUCCINATE;prednisolone 21-(hydrogen succinate);D1-Hydrocortisone 21-hemisuccinate;Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-, 21-(hydrogen succinate) (6CI, 7CI, 8CI);Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)- (9CI);Δ1-Hydrocortisone 21-hemisuccinate, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate, 1,4-Pregnadiene-11β,17,21-triol-3,20-dione 21-hemisuccinate;11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(4-oxo-4-hydroxybutyrate);21-(3-Carboxy-1-oxopropoxy)-11β,17-dihydroxypregna-1,4-diene-3,20-dione | | CAS: | 2920-86-7 | | MF: | C25H32O8 | | MW: | 460.52 | | EINECS: | 220-861-8 | | Product Categories: | RISPERDAL | | Mol File: | 2920-86-7.mol |  |
| | Prednisolone succinate Chemical Properties |
| Melting point | 206°C | | Boiling point | 485.35°C (rough estimate) | | alpha | [α]D20 +99～+104゜ (c=0.5, 1,4-dioxane) | | density | 1.1796 (rough estimate) | | refractive index | 1.4480 (estimate) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | | pka | 4.29±0.17(Predicted) | | form | Solid | | color | White to Off-White | | CAS DataBase Reference | 2920-86-7(CAS DataBase Reference) |
| | Prednisolone succinate Usage And Synthesis |
| Uses | Prednisolone hemisuccinate, is a metabolite of Prednisolone (P703740), which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. It is also the active metabolite of the drug prednisone. | | Uses | neuroleptic | | Definition | ChEBI: Prednisolone succinate is a hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. It has a role as an anti-inflammatory drug. It is a hemisuccinate, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisolone and a succinic acid. It is a conjugate acid of a prednisolone succinate(1-). |
| | Prednisolone succinate Preparation Products And Raw materials |
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