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| | N-Acetyl-L-phenylalanine Basic information |
| | N-Acetyl-L-phenylalanine Chemical Properties |
| Melting point | 171-173 °C(lit.) | | alpha | 40 º (c=1,methanol) | | Boiling point | 346.25°C (rough estimate) | | density | 1.1878 (rough estimate) | | refractive index | 40 ° (C=5, MeOH) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Solubility in methanol (almost transparency). Soluble in acetone and ethanol (20 mg/ ml). | | pka | 3.56±0.10(Predicted) | | form | Fine Crystalline Powder or Needles | | color | White to off-white | | optical activity | [α]22/D +40.0°, c = 1 in methanol | | InChIKey | CBQJSKKFNMDLON-JTQLQIEISA-N | | CAS DataBase Reference | 2018-61-3(CAS DataBase Reference) | | NIST Chemistry Reference | L-phenylalanine, n-acetyl-(2018-61-3) | | EPA Substance Registry System | L-Phenylalanine, N-acetyl- (2018-61-3) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | TSCA | Yes | | HS Code | 29242990 |
| | N-Acetyl-L-phenylalanine Usage And Synthesis |
| Chemical Properties | white to off-white fine cryst. powder or needles | | Uses | It is an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of aspartame. It is applied as an antidepressant. | | Uses | N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame. | | Definition | ChEBI: The N-acetyl derivative of L-phenylalanine. | | General Description | N-Acetyl-L-phenylalanine is an acetyl analog of L-phenylalanine. It is widely used as a reactant to synthesize methyl or ethyl esters of N-acetyl-L-phenylalanine, which are employed as versatile building blocks in peptide synthesis. | | Purification Methods | N-Acetyl-L-phenylalanine is recrystallised from H2O, 20% MeOH/H2O, or CHCl3; dry and store it at 4o. The (DL)-isomer crystallises from H2O, Me2CO, EtOAc, or CHCl3 with m 152-154o and the solubilities in w% at 25o are 0.73 (H2O), 4.3 (Me2CO), 0.79 (EtOAc) and 0.34 (CHCl3) [Kerr & Niemann J Org Chem 23 893 1958, Overby & Ingersoll J Am Chem Soc 73 3363 1951, L: Fu et al. J Am Chem Soc 76 6057 1954, Bender & Glasson J Am Chem Soc 81 1591 1959]. [Beilstein 14 I 238, 4 IV 1575.] |
| | N-Acetyl-L-phenylalanine Preparation Products And Raw materials |
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