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| | Dodecyl gallate Basic information |
| Product Name: | Dodecyl gallate | | Synonyms: | nipagallinla;Progallin LA;progallinla;n-dodecyl 3,4,5-trihydroxybenzoate;Lauryl Gallate (Dodecyl Gallate);DODECYL GALLATE( DODECYL 3,4,5-TRIHYDROXYBENZOATE);3mg/kg;96-97℃ | | CAS: | 1166-52-5 | | MF: | C19H30O5 | | MW: | 338.44 | | EINECS: | 214-620-6 | | Product Categories: | Aromatic Esters | | Mol File: | 1166-52-5.mol |  |
| | Dodecyl gallate Chemical Properties |
| Melting point | 94-97 °C (lit.) | | Boiling point | 394.57°C (rough estimate) | | density | 1.0677 (rough estimate) | | refractive index | 1.6120 (estimate) | | storage temp. | Store below +30°C. | | solubility | Very slightly soluble or practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride. | | form | neat | | pka | 7.93±0.25(Predicted) | | color | White to Almost white | | Odor | at 100.00?%. odorless | | Water Solubility | practically insoluble | | Sensitive | Air Sensitive | | BRN | 2701981 | | InChIKey | RPWFJAMTCNSJKK-UHFFFAOYSA-N | | LogP | 6.365 (est) | | CAS DataBase Reference | 1166-52-5(CAS DataBase Reference) | | NIST Chemistry Reference | Gallic acid, n-dodecyl ester(1166-52-5) | | EPA Substance Registry System | Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester (1166-52-5) |
| Hazard Codes | Xi | | Risk Statements | 43 | | Safety Statements | 24-37 | | RIDADR | 3335 | | WGK Germany | 1 | | RTECS | DH9100000 | | TSCA | Yes | | HS Code | 29182950 | | Toxicity | LD50 orally in Rabbit: 5000 mg/kg |
| | Dodecyl gallate Usage And Synthesis |
| Description | This gallate ester (E 310) is an antioxidant added to
foods and cosmetics to prevent oxidation of unsaturated
fatty acids. Cases have been reported in workers
in the food industry, gallate being contained in
margarine. It is also present in washing powder.
| | Chemical Properties | white to cream powder | | Uses | Dodecyl Gallate is an antioxidant used in cream cheese, instant
mashed potatoes, margarine, fats, and oils. | | Uses | Dodecyl 3,4,5-Trihydroxybenzoate is used in method for stabilizing the pH of an aqueous compound comprising drug. | | Uses | Dodecyl gallate is an antioxidant in cosmetic and pharmaceutical creams and emulsions, various fats, oils, waxes, and foods, such as margarine. | | Definition | ChEBI: Dodecyl gallate is a gallate ester. | | General Description | Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers. | | Contact allergens | This gallic acid ester (E 310) is an antioxidant added to
food and cosmetics to prevent oxidation of unsaturated
fatty acids. Cases were reported in workers of the food
industry, gallate being contained in margarine, and
from washing powder. | | Safety Profile | Poison by ingestion and
inhalation. Moderately toxic by skin contact. A
severe eye irritant. Questionable carcinogen with
experimental tumorigenic data. A pesticide. When
heated to decomposition it emits very toxic fumes
of NOx. | | Carcinogenicity | In a 2-year feeding study, with
the administration of up to 5 mg/kg of feed to rats, no increase
in tumor incidence was noted . In female mice, a dermal
injection of dodecyl gallate (100 nmol in 0.2mL acetone)
inhibits the formation of skin carcinomas and papillomas
induced by the tumor promoter phorbol myristate and the
initiator 7,12-dimethylbenz[a]anthracene . |
| | Dodecyl gallate Preparation Products And Raw materials |
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