|
| | 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Basic information |
| Product Name: | 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside | | Synonyms: | 2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside;EH-201;Tetrahydroxystilbene glucoside;THSG;CHEMBL460860;Astragalus polyphenols;2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid;2,3,4,5-Tetrahydroxystilbene 2-glucoside | | CAS: | 82373-94-2 | | MF: | C20H22O9 | | MW: | 406.39 | | EINECS: | 683-231-5 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors | | Mol File: | 82373-94-2.mol |  |
| | 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Chemical Properties |
| Boiling point | 715.0±60.0 °C(Predicted) | | density | 1.593±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: soluble5mg/mL, clear (warmed) | | form | powder | | pka | 8.78±0.40(Predicted) | | color | white to brown | | CAS DataBase Reference | 82373-94-2 |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 29389090 |
| | 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Usage And Synthesis |
| Uses | 2,3,4'',5-Tetrahydroxystilbene 2-O-Glucoside is a scavenging agent, that attenuates free radicals and upregulate antioxidant?/detoxifying enzymes to protect against oxidative damage. It also protects UB/OC-2 cells from H2O2-induced autophagy and apoptosis in vitro. | | Definition | ChEBI: (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside is a stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. It has a role as an antioxidant, a cyclooxygenase 2 inhibitor, an anti-inflammatory agent, a cardioprotective agent, a platelet aggregation inhibitor and an apoptosis inhibitor. It is a stilbenoid, a beta-D-glucoside and a member of resorcinols. | | General Description | 2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol. | | Biochem/physiol Actions | 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models. | | Physiological effects | Stilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis. |
| | 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Preparation Products And Raw materials |
|
