7-Epitaxol

7-Epitaxol Basic information
Product Name:7-Epitaxol
Synonyms:7-epi-Paclitaxel(7-Epitaxol);Benzenepropanoicacid,beta-(benzoylaMino)-alpha-hydroxy-,6,12B-bis(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-ylester,(2ar-(;Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2ar,4R,4as,6R,9S,11S,12S,12ar,12bs)-6,12B-bis(acetyloxy)-12-(benzoyloxy)- 2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-yl ester, (alphar,betas)-;Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12B-bis(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-yl ester, (2ar- (2aalpha,4alpha,4abeta,6beta,9alpha(alphar*,betas*),11alpha,12alpha,12aalpha,12balpha))-;Epitaxol;7-Epitaxol 7-Epipaclitaxel;7-Epipaclitaxel, froM Taxus chinensis;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid derivative
CAS:105454-04-4
MF:C47H51NO14
MW:853.91
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;Aromatics;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:105454-04-4.mol
7-Epitaxol Structure
7-Epitaxol Chemical Properties
Melting point 168-170?C
Boiling point 957.1±65.0 °C(Predicted)
density 1.39±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Inert atmosphere,2-8°C
solubility DMF: 25 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
pka11.90±0.20(Predicted)
Safety Information
HS Code 29329990
MSDS Information
7-Epitaxol Usage And Synthesis
Chemical PropertiesOff-White to Pale Yellow Solid
UsesThe compund has been isolated from Taxus brevifolia. It is an antineoplastic that is currently being used in cancer research. Paclitaxel EP Impurity E.
Uses7-Epitaxol has been isolated from Taxus brevifolia. It is an antineoplastic that is currently being used in cancer research. Paclitaxel EP Impurity E.
7-Epitaxol Preparation Products And Raw materials
Forskolin Cephalomannine Paclitaxel IMpurity F Baccatine III N-Debenzoyl-N-[(3E)-hex-3-enoyl]paclitaxel NITINE(BENZYL ANALOG OF TAXOL)(P) β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)Methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetraMethyl-12-oxo-6,10-Methanobenzocyclodecen-8-yl Ester Paclitaxel EP Impurity I ACETYLTAXOL, 7-(P) 7-EPI-10-DEACETYLTAXOL 7-EPI-CEPHALOMANNINE Deacetyltaxol Paclitaxel EP Impurity J Camphor benzalkonium methosulfate 7-O-(Triethylsilyl) Paclitaxel PACLITAXEL C Paclitaxel IMpurity O TRANS-1,2-CYCLOOCTANEDIOL

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