1-Amino-2-methylpropan-2-ol

1-Amino-2-methylpropan-2-ol Basic information
Product Name:1-Amino-2-methylpropan-2-ol
Synonyms:1-Amino-2-methylpropan-2-ol;Amino-2-methyl-2-propanol, 1-;1-Amino-2-methyl-2-propanol;1-azanyl-2-methyl-propan-2-ol;1,1-Dimethylethanolamine;2-Amino-a,a-dimethylethanol;2-Hydroxy-2-methyl-1-propylamine;2-Hydroxyisobutylamine
CAS:2854-16-2
MF:C4H11NO
MW:89.14
EINECS:
Product Categories:pharmacetical
Mol File:2854-16-2.mol
1-Amino-2-methylpropan-2-ol Structure
1-Amino-2-methylpropan-2-ol Chemical Properties
Melting point 8.72°C (estimate)
Boiling point 151°C(lit.)
density 1.915 g/mL at 25 °C
refractive index n20/D1.448
Fp 73℃
storage temp. 2-8°C
solubility Chloroform, Ethyl Acetate (Slightly)
pka12.99±0.50(Predicted)
form Oil
color Clear Colourless
InChIInChI=1S/C4H11NO/c1-4(2,6)3-5/h6H,3,5H2,1-2H3
InChIKeyLXQMHOKEXZETKB-UHFFFAOYSA-N
SMILESC(N)C(C)(O)C
CAS DataBase Reference2854-16-2
NIST Chemistry Reference1-Amino-2-methyl-2-propanol(2854-16-2)
Safety Information
Hazard Codes Xn
Risk Statements 22-37/38-41
Safety Statements 26-39
RIDADR 1993
WGK Germany 3
RTECS UA6125000
HazardClass IRRITANT
PackingGroup 
HS Code 2922190090
MSDS Information
1-Amino-2-methylpropan-2-ol Usage And Synthesis
Chemical PropertiesPale yellow liquid
Uses3-Amino-2-methyl-2-propanol, is a versatile intermediate used for the synthesis of more complex compounds, including inhibitors. It is an intermediate in the preparation of metabolites of Darunavir (D193500), such as (A581405).
1-Amino-2-methylpropan-2-ol Preparation Products And Raw materials
Preparation ProductsN-(2-hydroxy-2-methylpropyl)acetamide-->Urea, N-[(1R)-1-[[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-diMethyl-1-piperidinyl]carbonyl]-2-Methylpropyl]-N'-(2-hydroxy-2-Methylpropyl)--->α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-->2-Methyl-1-(tetrahydro-pyran-4-ylamino)-propan-2-ol-->MFCD00086567
Betaine 2-HYDROXY-2-METHYLPROPANOHYDRAZIDE 1-Amino-2-methylpropan-2-ol ALLOXANTIN Tiglic aldehyde 5,5-Dimethyloxazolidine-2,4-dione ALTRENOGEST BENZILIC HYDRAZIDE 3-phenylpyrrolidin-3-ol 1-AMINOMETHYL-1-CYCLOHEXANOL HYDROCHLORIDE CYTOCHALASIN E Glycine Hexocyclium BENZILAMIDE CYTOCHALASIN A VERATRINE AMINO ACIDS N,N-Dimethyl-1,4-phenylenediamine

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