PERAKINE

PERAKINE Basic information
Product Name:PERAKINE
Synonyms:PERAKINE;(13R)-13-Acetyloxy-7aα,2α,6α-ethan[1]yl[2]ylidene-1,2,3,4,6,7,7a,12bβ-octahydro-4α-methylindolo[2,3-a]quinolizine-3β-carbaldehyde;(17R,20α)-19-Oxo-1,2-didehydro-1-demethyl-21β-methyl-18-norajmalan-17-ol acetate;18-Norajmalan-19-al, 17-(acetyloxy)-1,2-didehydro-1-demethyl-21-methyl-, (17R,20A,21B)-;Aids003043;Aids-003043;Indole alkaloid;Raucaffrine
CAS:4382-56-3
MF:C21H22N2O3
MW:350.42
EINECS:
Product Categories:
Mol File:4382-56-3.mol
PERAKINE Structure
PERAKINE Chemical Properties
Melting point 186 °C
Boiling point 492.8±45.0 °C(Predicted)
density 1.59±0.1 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka5.38±0.70(Predicted)
Safety Information
MSDS Information
PERAKINE Usage And Synthesis
DescriptionThis alkaloid has been shown to be identical with Perakine (q.v.).
UsesPerakine is an alkaloid extracted from family of Rauvolfia plants which acts as an inhibitor of aldose reductase, a potent drug target for diabetes.
DefinitionChEBI: An indole alkaloid having a ajmalan-type skeleton and characterised by a 17alpha-acetoxy group, a 21beta-methyl group, loss of the 1-methyl group with associated unsaturation at N(1)2C(2), and a 20alph -formyl group in place of the 20beta-ethyl side-chain.
ReferencesKhan, Khan, Siddiqui., Pakistan 1. Sci. Ind. Res., 8, 23 (1965)
PERAKINE Preparation Products And Raw materials
Daurinoline Xanthiazone veratramine VERATRIDINE Xanthiside L-Hyoscyamine daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one VERATRINE menisdaurin Ajmaline

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