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| | epothilone E Basic information |
| Product Name: | epothilone E | | Synonyms: | epothilone E;[4S,7R,8S,9S,13R,14S,16S(E)]-13,14-Epoxy-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[2-[2-(hydroxymethyl)thiazol-4-yl]-1-methylvinyl]-1-oxacyclohexadecane-2,6-dione;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-14-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-5,7,9,9-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione;4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)-;epothilone E USP/EP/BP | | CAS: | 201049-37-8 | | MF: | C26H39NO7S | | MW: | 509.66 | | EINECS: | | | Product Categories: | | | Mol File: | 201049-37-8.mol |  |
| | epothilone E Chemical Properties |
| Boiling point | 715.5±60.0 °C(Predicted) | | density | 1.187±0.06 g/cm3(Predicted) | | pka | 13.15±0.10(Predicted) |
| | epothilone E Usage And Synthesis |
| Uses | Epothilone E is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant. |
| | epothilone E Preparation Products And Raw materials |
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