2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER

2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Basic information

Product Name:	2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms:	IFLAB-BB F1018-1557;ETHYL 2-AMINO-4-PHENYL-3-THIOPHENECARBOXYLATE;ETHYL 2-AMINO-4-PHENYLTHIOPHENE-3-CARBOXYLATE;CHEMBRDG-BB 3000514;AURORA 20210;BUTTPARK 30\06-09;ART-CHEM-BB B000514;2-AMINO-4-PHENYL-3-THIOPHENECARBOXYLIC ACID, ETHYL ESTER
CAS:	4815-36-5
MF:	C13H13NO2S
MW:	247.31
EINECS:
Product Categories:
Mol File:	4815-36-5.mol

2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties

Melting point	92-97 °C
Boiling point	391.0±42.0 °C(Predicted)
density	1.231
storage temp.	2-8°C(protect from light)
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 20 mg/ml
form	A crystalline solid
pka	-0.14±0.10(Predicted)
CAS DataBase Reference	4815-36-5(CAS DataBase Reference)

Safety Information

MSDS Information

2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Usage And Synthesis

Chemical Properties	Yellow solid
Uses	2-Amino-4-phenyl-thiophene-3-carboxylic acid ethyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Uses	Ethyl 2-Amino-4-phenylthiophene-3-carboxylate is used in the design and synthesis of thieno[2,3-d]pyrimidine analogs which exhibits antiproliferative activity against human cancer cells such as liver, pancreatic and colorectal cancer.

2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials	Ethanol-->Acetic acid-->Benzene-->Sulfur-->Ethyl cyanoacetate-->Diethylamine-->Acetophenone-->Ammonium acetate
Preparation Products	4-CHLORO-5-PHENYLTHIENO[2,3-D]PYRIMIDINE-->2-(2-CYANO-ACETYLAMINO)-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER-->ethyl 2-acetamido-4-phenylthiophene-3-carboxylate-->Thieno[2,3-d]pyrimidin-4(1H)-one, 3-cyclohexyl-2,3-dihydro-5-phenyl-2-thioxo--->4-phenyl-2-Thiophenamine-->2-Benzyl-4-chloro-5-phenylthieno[2,3-d]pyriMidine

Login