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| | Risedronic acid Basic information |
| Product Name: | Risedronic acid | | Synonyms: | 1-Hydroxy-2-(3-pyridyl)-ethan-1,1-bis-phosphonic acid;RISEDRONIC ACID: RISEDRONIC ACID MONOHYDRATE;1-Hydroxy-2-(3-pyridinyl)ethylidenebisphosphonicacidmonohydrate;1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE]BISPHOSPHONIC ACID;3-(Acetic acid)Pyridine;Phosphonic acid,P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-;P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-phosphonic acid;Risedronic acid (Actonel) | | CAS: | 105462-24-6 | | MF: | C7H11NO7P2 | | MW: | 283.11 | | EINECS: | 600-654-2 | | Product Categories: | API;(intermediate of risedronate sodium;Risedronate | | Mol File: | 105462-24-6.mol |  |
| | Risedronic acid Chemical Properties |
| | Risedronic acid Usage And Synthesis |
| Uses | Risedronic Acid is a pyridinyl biphosphonate bone resorption inhibitor. It is a potentially useful biophosphonate for bone resorption analysis. | | Definition | ChEBI: Risedronic acid is a member of pyridines. It is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease. It functions by preventing resorption of bone. | | Mode of action | Risedronatic acid binds to bone hydroxyapatite. Bone resorption causes local acidification, releasing risedronic acid which is that taken into osteoclasts by fluid-phase endocytosis. Endocytic vesicles are acidified, releasing risedronic acid to the cytosol of osteoclasts where they induce apoptosis through inhbition of farnesyl pyrophosphate synthase. Inhibition of osteoclasts results in decreased bone resorption. |
| | Risedronic acid Preparation Products And Raw materials |
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