Ethyl 3-benzoylacrylate

Ethyl 3-benzoylacrylate Basic information
Product Name:Ethyl 3-benzoylacrylate
Synonyms:Ethyl 3-benzoylacrylate, HPLC 92%;3-Benzoyl Acrylic Acid Ethyl Ester;ETHYL 3-BENZOYLACRYLATE, TECH., 92%;ethyl e-benzoylacrylate;trans-3-Benzoylacrylicacidethylester~Ethyltrans-4-oxo-4-phenyl-2-butenoate;Enalapril Impurity 7;Ethyl 3-benzoylacrylate, tech., containing ca. 3% cis-isomer, 93%;E3BA
CAS:17450-56-5
MF:C12H12O3
MW:204.22
EINECS:621-286-9
Product Categories:Aromatic Aldehydes & Derivatives (substituted);C12 to C63;Pharmaceutical Intermediates;Carbonyl Compounds;Esters
Mol File:17450-56-5.mol
Ethyl 3-benzoylacrylate Structure
Ethyl 3-benzoylacrylate Chemical Properties
Melting point 32 °C
Boiling point 184-185 °C/25 mmHg (lit.)
density 1.112 g/mL at 25 °C (lit.)
refractive index 1.542-1.546
Fp 88°C
storage temp. Sealed in dry,Room Temperature
Specific Gravity1.112
BRN 2210035
InChIKeyACXLBHHUHSJENU-HJWRWDBZSA-N
CAS DataBase Reference17450-56-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 24/25-37/39-26-36
RIDADR UN2810
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 29183000
MSDS Information
ProviderLanguage
ACROS English
ALFA English
Ethyl 3-benzoylacrylate Usage And Synthesis
Chemical Propertiesclear yellow liquid
UsesEthyl 3-benzoylacrylate is an impurity of Enalapril (E555250), an?antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor.
Synthesis Reference(s)Tetrahedron Letters, 13, p. 407, 1972 DOI: 10.1016/S0040-4039(01)84337-9
General DescriptionEthyl 3-benzoylacrylate (ethyl trans-3-benzoylacrylate) undergoes enantioselective guanidine catalyst promoted Michael addition reaction with dithranol to yield Michael adduct.
Ethyl 3-benzoylacrylate Preparation Products And Raw materials
Preparation ProductsRamipril
Ethyl 3-benzoylacrylate Trinexapac-ethyl Ethanol Ethyl pyruvate Ethyl formate Triethyl phosphonoacetate 2-Hydroxyethyl methacrylate Ethylparaben POLY(ETHYL METHACRYLATE) ISOXADIFEN-ETHYL Ethyl acetate Ethyl trans-3-Benzoylacrylate 2-Hydroxyethyl acrylate Ethyl acrylate POLY(ETHYL ACRYLATE) ETHYL 2-CYANOACRYLATE Ethyl methacrylate Ethyl cyanoacetate

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