ChemicalBook Product Catalog Biochemical Engineering Polypeptide SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA

SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA

SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Basic information
Product Name:SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA
Synonyms:SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA;SUBSTANCE P ACETATE SALT HYDRATE;Substance P hydrate acetate salt;SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA USP/EP/BP
CAS:137348-11-9
MF:C65H102N18O15S
MW:1407.7
EINECS:251-545-8
Product Categories:AgonistPeptides for Cell Biology;TachykininsObesity Research;Neuropeptides;Neurotransmission (Obesity);Peptides for Cell Biology;Tachykinins
Mol File:137348-11-9.mol
SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Structure
SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Chemical Properties
storage temp. −20°C
solubility 0.1 M acetic acid: soluble1mg/mL
form powder
color white
BRN 5153552
Safety Information
WGK Germany 3
MSDS Information
SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Usage And Synthesis
UsesSubstance P acetate salt hydrate has been:
  • used as a neurokinin 1 (NK1) receptor agonist for the activation of spinal nociceptive circuitry in mice
  • administered in central nucleus (ACE) in rat to study its positive reinforcing effects
  • used as an inhibitor of myosin light chain kinase in isolated lymphatic vessels from rat

General DescriptionSubstance P is a small peptide produced by macrophages, lymphocytes, eosinophils, dendritic cells and nerves. It is part of the neurokinin group.
Biochem/physiol ActionsNK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.
SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Preparation Products And Raw materials
ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 3ACOH 5H2O FAM-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-GLY-LYS-ARG SUBSTANCE P, TAMRA-LABELED
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