cefaloram

cefaloram Basic information
Product Name:cefaloram
Synonyms:cefaloram;Cephalosporin G;(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(7R)-3-(Acetoxymethyl)-7β-[(α-oxophenethyl)amino]cepham-3-ene-4-carboxylic acid;(7R)-7-(Phenylacetylamino)-3-(acetoxymethyl)cepham-3-ene-4-carboxylic acid;(6R,7R)-3-(acetoxymethyl)-8-keto-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-(2-phenylethanoylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS:859-07-4
MF:C18H18N2O6S
MW:390.41
EINECS:212-725-1
Product Categories:
Mol File:859-07-4.mol
cefaloram Structure
cefaloram Chemical Properties
Melting point 160-162 °C (decomp)
Boiling point 742.8±60.0 °C(Predicted)
density 1.48±0.1 g/cm3(Predicted)
pka2.68±0.50(Predicted)
Safety Information
MSDS Information
cefaloram Usage And Synthesis
DefinitionChEBI: Cefaloram is a cephalosporin derivative with potent antibacterial activity which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division, inactivation of which interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in the weakening of the bacterial cell wall and causing cell lysis. It has a role as an antibacterial drug.
cefaloram Preparation Products And Raw materials
cefaloram 3-ACETOXYMETHYL-7-AMINO-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID Hydroxymethyl-7-Aminocephalosporanic acid 7-Amino-3-methoxy-3-cephem-4-carboxylic acid 7-Aminocephalosporanic acid cefaloglycin 7-AMCA 7-Phenyl-acetamido-deacetoxy-cephalosporanic-acid

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