(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Basic information
Product Name:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol
Synonyms:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol;(1S)-1-[(3-hydroxy-4-methoxy-phenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;(S)-Reticuline;reticuline;[1S,(+)]-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol;[1S,(+)]-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinoline-7-ol;2-Methoxy-5-[[(1S)-2-methyl-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline]-1-ylmethyl]phenol;Reticuline (>90% ee)
CAS:485-19-8
MF:C19H23NO4
MW:329.39
EINECS:207-611-3
Product Categories:Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:485-19-8.mol
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Structure
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Chemical Properties
Melting point 125-126°C
Boiling point 648.96°C (rough estimate)
density 1.4371 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Soluble in DMSO
pka9.95±0.10(Predicted)
Safety Information
MSDS Information
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesPrecursor of many aporphine and morphine-type alkaloids.
UsesReticulin can be used to improve production of morphinan alkaloids, as well as its anti-inflammatory properties. It can also be used to lead scaffolds as PDE5A inhibitors and antihypertensives.
DefinitionChEBI: The (S)-enantiomer of reticuline.
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Preparation Products And Raw materials
Raw materialsIsoquinoline, 1,2,3,4-tetrahydro-6-methoxy-1-[[4-methoxy-3-(phenylmethoxy)phenyl]methyl]-2-methyl-7-(phenylmethoxy)-, (S)- (9CI)-->Cocculanorine (6CI,8CI)-->Isovanillin
ESCHSCHOLTZINE HCL (-)-BETA-HYDRASTINE BULBOCAPNINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE (+)-MENISPERINE IODIDE NOSCAPINE HYDROCHLORIDE (+)-CORYDALINE TIMTEC-BB SBB006457 ISOCORYDINE HYDROCHLORIDE (-)-STYLOPINE (-)-BICUCULLINE METHOCHLORIDE (+)-BULBOCAPNINE L-TETRANDRINE Narcotine CALIFORNIDINE PERCHLORATE NOSCAPINE HYDROCHLORIDE HYDRATE BOLDINE DIMETHYL ETHER AKOS 208-02

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