Prednisolone 21-trimethylacetate

Prednisolone 21-trimethylacetate Basic information
Product Name:Prednisolone 21-trimethylacetate
Synonyms:11β,17-Dihydroxy-21-(2,2-dimethyl-1-oxopropoxy)pregna-1,4-diene-3,20-dione;21-(Pivaloyloxy)-11β,17-dihydroxypregna-1,4-diene-3,20-dione;[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 2,2-dimethylpropanoate;[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] 2,2-dimethylpropanoate;2,2-dimethylpropionic acid [2-(11,17-dihydroxy-3-keto-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-keto-ethyl] ester;21-Trimethylacetate;prednisolone 21-pivalate;mecortolon
CAS:1107-99-9
MF:C26H36O6
MW:444.56044
EINECS:214-172-1
Product Categories:
Mol File:1107-99-9.mol
Prednisolone 21-trimethylacetate Structure
Prednisolone 21-trimethylacetate Chemical Properties
Melting point 233-236°
alpha D26 +103° (c = 1.208 in chloroform); D20 +97.5° (c = 1 in chloroform)
Boiling point 597.3±50.0 °C(Predicted)
density 1.23±0.1 g/cm3(Predicted)
solubility Practically insoluble in water, slightly soluble in ethanol (96 per cent), soluble in methylene chloride.
pka12.34±0.70(Predicted)
form neat
Stability:Moisture Sensitive
CAS DataBase Reference1107-99-9
Safety Information
MSDS Information
Prednisolone 21-trimethylacetate Usage And Synthesis
Chemical PropertiesWhite or almost white, crystalline powder.
UsesPrednisolone Pivalate is a metabolite of Prednisolone (P703740), which is a synthetic corticosteroid; metabolically interconvertible with prednisone.
UsesGlucocorticoid.
Prednisolone 21-trimethylacetate Preparation Products And Raw materials
11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate 3-Methylbutyl 3-methylbutanoate Deprodone Prednisolone 21-trimethylacetate Prednisolone 9E,12Z-Tetradecadien-1-yl-acetate DODECYL ISOBUTYRATE Meprednisone Prednisone hexyl pivalate Prednisolone-21-acetate

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