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| | mexazolam Basic information |
| Product Name: | mexazolam | | Synonyms: | mexazolam;10-Chloro-2,3,7,11b-tetrahydro-3-methyl-11b-(o-chlorophenyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one;CS 386;Melex;Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl- (9CI);10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one;10-Chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one;10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one | | CAS: | 31868-18-5 | | MF: | C18H16Cl2N2O2 | | MW: | 363.24 | | EINECS: | | | Product Categories: | | | Mol File: | 31868-18-5.mol |  |
| | mexazolam Chemical Properties |
| Melting point | 172-175° | | Boiling point | 522.2±50.0 °C(Predicted) | | density | 1.3817 (rough estimate) | | refractive index | 1.6100 (estimate) | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 6.69(at 25℃) | | color | White to Off-White |
| Toxicity | LD50 in male, female mice; male, female rats (mg/kg): 4687, 4571, 810, 4500 orally; >6000, >6000, >4000, >4000 i.p. or s.c. (Masuda) |
| | mexazolam Usage And Synthesis |
| Description | Mexazolam is a benzodiazepine anxiolytic closely related to flutazolam. It is
reported to be particularly effective against psychosomatic essential hypertension,
peptic ulcer, irritable colon and autonomic dystonia. | | Originator | Sankyo (Japan) | | Uses | Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway. | | Definition | ChEBI: Mexazolam is an oxazolobenzodiazepine and a hemiaminal ether. | | Brand name | MELEX |
| | mexazolam Preparation Products And Raw materials |
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