BRUSATOL

BRUSATOL Basic information
Physical Form Description
Product Name:BRUSATOL
Synonyms:BRUSATOL;Regaloside B;β-D-Glucopyranoside, (1S)-2-(acetyloxy)-1-[[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]methyl]ethyl
CAS:114420-67-6
MF:C20H26O11
MW:442.41
EINECS:
Product Categories:
Mol File:114420-67-6.mol
BRUSATOL Structure
BRUSATOL Chemical Properties
Boiling point 727.5±60.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka8.58±0.15(Predicted)
CAS DataBase Reference114420-67-6
Safety Information
MSDS Information
BRUSATOL Usage And Synthesis
Physical FormPowder
DescriptionBrusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor erythroid 2-related factor 2 (Nrf2) and is capable of inducing a variety of biological effects. The effects of Brusatol on oocyte meiosis has not been addressed.
UsesClinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation.
BRUSATOL Preparation Products And Raw materials
PULCHINENOSIDE B4 [(S)-2-[(3,4-Dihydroxy-trans-cinnamoyl)oxy]-3-hydroxypropyl]β-D-glucopyranoside 7,8-Dihydroxycoumarin Potassium pyrophosphate Benzothiazole GLUCOSYLRUTIN Brusatol regalosideG Cyclohexane-1,2,3,4,5,6-hexol 3-(4-Hydroxyphenyl)propenoic acid (2R)-1-(β-D-glucopyranosyloxy)-3-hydroxypropan-2-yl ester regaloside K Anemoside A3 Pulchinenoside A3 2,4-Dihydroxyacetophenone 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE Menadione Pulsatilla saponin D D-tagatose Azelaic acid

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