SAUCHINONE

SAUCHINONE Basic information
Product Name:SAUCHINONE
Synonyms:(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill;SAUCHINONE;(5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro- 5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one;5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-;Sauchinone >=98% (HPLC);AI3 00896
CAS:177931-17-8
MF:C20H20O6
MW:356.37
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:177931-17-8.mol
SAUCHINONE Structure
SAUCHINONE Chemical Properties
Melting point 224-226℃
Boiling point 498.1±45.0 °C(Predicted)
density 1.43±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
solubility DMSO: soluble5mg/mL, clear (warmed)
form powder
color white to beige
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29329990
MSDS Information
SAUCHINONE Usage And Synthesis
UsesSauchinone is a lignan first isolated from the aerial parts of S. chinensis, a plant used in Asian medicine for its anti-inflammatory, anti-angiogenic, and anti-nociceptive activities. Sauchinone has numerous effects on isolated cells, including blocking NF-κB activation in LPS-stimulated macrophages, inducing heme oxygenase-1 transcription in endothelial cells, and attenuating oxidative-stress-induced damage in myoblasts. Sauchinone is extensively metabolized in vivo, but intraperitoneal administration significantly reduces myocardial infarct size induced by ischemia/reperfusion in mice.
SAUCHINONE Preparation Products And Raw materials
Sanggenon C Notoginsenoside R1 Cephalomannine MORIN ARTEMISININ 7,8-Dihydroxycoumarin Maslinic acid Complanatoside A MONOCROTALINE Carboxyatractyloside spicatosideB SHANZHISIDE METHYL ESTER KAEMPFEROL-3-O-RUTINOSIDE Alpinetin Evodiamine dendrobine Cornuside 3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID

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