Fucoxanthin

Fucoxanthin Basic information
Product Name:Fucoxanthin
Synonyms:Fucoxanthin, froM LaMinariajaponicaAresch;Fucoxanthin solution;6'R,7'-didehydro-5R,6-epoxy-4',5',6S,7-tetrahydro-3S,3'S,5'R-trihydroxy-β,β-caroten-8(5H)-one;Fucoxanthin, 98%, from Laminaria japonica Aresch;(3S,3'S,5R,5'R,6S,6'R)-6',7'-Didehydro-5,6-epoxy-4',5',6,7-tetrahydro-3,3',5'-trihydroxy-,-caroten-8(5H)-one;all-trans-Fucoxanthin;Fucoxanthin DISCONTINUED;(3S,3'S,5R,5'R,6S,6'R)-
CAS:3351-86-8
MF:C42H58O6
MW:658.91
EINECS:200-486-6
Product Categories:Herb extract;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:3351-86-8.mol
Fucoxanthin Structure
Fucoxanthin Chemical Properties
Melting point 166-168°C
alpha D18 +72.5 ±9° (chloroform)
Boiling point 590.43°C (rough estimate)
density 1.09
refractive index n20/D1.360-1.362
Fp 14℃
storage temp. -20°C
solubility Ethanol,
pka14.47±0.60(Predicted)
form neat
color Crystalline
λmaxλ: 444-454 nm Amax
InChIKeySJWWTRQNNRNTPU-WEAAWPSVSA-N
LogP7.830 (est)
CAS DataBase Reference3351-86-8(CAS DataBase Reference)
Safety Information
Hazard Codes F
Risk Statements 11
Safety Statements 7-16-24/25
RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany 3
HS Code 29153900
MSDS Information
Fucoxanthin Usage And Synthesis
DescriptionFucoxanthin is another important xanthophyll. It is widely found in heterokontophyta, such as brown algae and oceanic microalgae,and is believed be the second-most abundant carotenoid on Earth after β-carotene. Recently, studies on the functionality of fucoxanthin have been increasingly conducted,and fucoxanthin has been shown to possess various beneficial physiological activities.It has various pharmaceutical effects such as anti-tumor, anti-inflammatory, anti-oxidant, anti-obesity effects, protecting nerve cell, increasing the content of ARA(arachidonic acid) and DHA (docosahexaenoic acid) in mice; It is widely used as medicine, skin care and beauty industry, and in the Food supplements market.
Chemical PropertiesFucoxanthin is an orange-colored pigment, along with chlorophylls a and c and β-carotene, present in Chromophyta (Heterokontophyta or Ochrophyta), including brown seaweeds (Phaeophyceae) and diatoms (Bacillariophyta). It is insoluble in water but soluble in organic solvents such as ethanol; it is typically lipid-soluble powder or oil.
UsesFucoxanthin is a carotenoid pigment found in fresh brown algae.It can be used as an anti-obesity, anticancer, anti-cholesterol, and anti-diabetic agent and as a food colorant, but it is very unstable. It is easily affected by heating, aerial exposure, and illumination.
UsesFucoxanthin is a carotenoid that occurs naturally in certain algae. It significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet. Fucoxanthin increases the amount of mitochondrial uncoupling protein 1 (UCP1), a fatty acid-stimulated protein involved in respiration and thermogenesis in WAT of mice and rats. In KK-Ay mice, which are used to model obese type 2 diabetics with hyperinsulinemia, fucoxanthin reduces WAT gain and also decreases blood glucose and plasma insulin levels.
UsesFucoxanthin has been used to study its neuroprotective effects. It has also been used in calibration to identify the most efficient fucoxanthin producing strains of microalgae.
DefinitionChEBI: A natural product found in Sporochnus comosus.
General DescriptionFucoxanthin is isolated from brown algae. It has anti-angiogenic, hepatoprotective,?cardiovascular and cerebrovascular protective properties. Fucoxanthin stimulates G1 cell-cycle arrest and apoptosis in cancer cell lines.
Biochem/physiol ActionsXanthophyll carotenoid pigment extracted from algae. Exhibits anticancer, antioxidant, anti-obesity and anti-inflammatory properties.
Fucoxanthin Preparation Products And Raw materials
Astaxanthin Sodium alginate CAROTENOID MIXED STANDARD 500UL(SH) PROPOLIS EXTRACT FROM PENNSYLVANIA CHLOROPHYLL Punicalagin Corosolic acid BETA-GLUCAN HEXA-4,5-DIEN-1-OL Fucoxanthin 2,3-PENTADIENE β-Carotene Carotene ACETIC ACID CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTER 3,5,7-Nonatrien-2-one 3-METHYL-1,2-BUTADIENE hepta-1,2-diene 1,2-PENTADIENE

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