ChemicalBook Product Catalog Chemical Reagents Organic reagents Amide PHTHALAMIC ACID

PHTHALAMIC ACID

PHTHALAMIC ACID Basic information
Product Name:PHTHALAMIC ACID
Synonyms:2-(Aminocarbonyl)benzoic acid;Phthalamic acid ,99%;2-Carbamoylbenzoic acid;o-Carbamoylbenzoic acid;Phthalamide acid;Phthalic acid monoamide;Phthalic monoamide;Phthalamic acid 97%
CAS:88-97-1
MF:C8H7NO3
MW:165.15
EINECS:201-871-1
Product Categories:C8;Carbonyl Compounds;Carboxylic Acids;Building Blocks;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks
Mol File:88-97-1.mol
PHTHALAMIC ACID Structure
PHTHALAMIC ACID Chemical Properties
Melting point 140-143 °C(lit.)
Boiling point 394.2±25.0 °C(Predicted)
density 1.368
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka3.75±0.10(Predicted)
form Solid
color White to Off-White
BRN 1868205
CAS DataBase Reference88-97-1(CAS DataBase Reference)
EPA Substance Registry SystemBenzoic acid, 2-(aminocarbonyl)- (88-97-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA Yes
HazardClass IRRITANT
HS Code 2924297099
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
PHTHALAMIC ACID Usage And Synthesis
UsesPhthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity.
UsesPhthalamic acid may be used to synthesize anthranilic acid via reaction with sodium hypochlorite.
DefinitionChEBI: 2-carbamoylbenzoic acid is a carbamoylbenzoic acid.
General DescriptionPhthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (kobs) as 5.1×10-5sec-1 at pH 1.3-1.8 and 35°C. It undergoes hydrolysis about 105 times faster than benzamide.
PHTHALAMIC ACID Preparation Products And Raw materials
Raw materialsHydrochloric acid-->Potassium hydroxide-->Phthalimide-->Silver nitrate
Preparation ProductsBentazone
N-Metatolyl phthalamic acid PHTHALAMIC ACID TIMTEC-BB SBB007539 2-{[(3-CHLOROPHENYL)AMINO]CARBONYL}-BENZOIC ACID 2-[(4-FLUOROPHENYL)CARBAMOYL]-BENZOIC ACID Phthalylsulfathiazole N-(2,3-DIMETHYL-PHENYL)-PHTHALAMIC ACID N-(4-(acetylsulphamoyl)phenyl)phthalamic acid PHTHALANILLIC ACID N-(2,5-DIMETHYL-PHENYL)-PHTHALAMIC ACID 2-[(4-chlorophenyl)carbamoyl]benzoic acid 2-[[(2-CHLOROPHENYL)AMINO]CARBONYL]-BENZOIC ACID 2-([(4-IODOPHENYL)AMINO]CARBONYL)BENZOIC ACID N-BENZYL-PHTHALAMIC ACID 2-([(4-ETHYLPHENYL)AMINO]CARBONYL)BENZOIC ACID 4'-SULFAMOYLPHTHALANILIC ACID Ftaxilide AKOS BBS-00004780
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