Coumarin 6

Coumarin 6 Basic information

Product Name:	Coumarin 6
Synonyms:	3-(2-Benzothiazolyl)-7-(diethylamino)-2H-1-benzopyran-2-one;3-(Benzothiazol-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one;7-(Diethylamino)-3-(2-benzothiazolyl)-2H-1-benzopyran-2-one;7-(Diethylamino)-3-(benzothiazole-2-yl)-2H-1-benzopyran-2-one;3-(2-Nenzothiazolyl)-7-(diethylamino)coumarin;Coumarin 6,98%,pure,laser grade;Coumarin 6 ,98%;Coumarine 6
CAS:	38215-36-0
MF:	C20H18N2O2S
MW:	350.43
EINECS:	253-830-2
Product Categories:	electronic;Electroluminescence;Functional Materials
Mol File:	38215-36-0.mol

Coumarin 6 Chemical Properties

Melting point	208-210 °C (lit.)
Boiling point	570.1±60.0 °C(Predicted)
density	1.1830 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMF: soluble
form	Powder
pka	2.98±0.20(Predicted)
color	Orange
Water Solubility	NEGLIGIBLE
BRN	1085798
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	38215-36-0(CAS DataBase Reference)
EPA Substance Registry System	2H-1-Benzopyran-2-one, 3-(2-benzothiazolyl)-7-(diethylamino)- (38215-36-0)

Safety Information

Hazard Codes	Xn,C
Risk Statements	20/21/22-36/37/38-34
Safety Statements	22-24/25-37/39-26-45-36/37/39-27
WGK Germany	3
F	8
HS Code	29329990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

Coumarin 6 Usage And Synthesis

Chemical Properties	orange crystalline powder
Uses	Coumarin 6 is a member of 7-aminocoumarins. It has a role as a fluorochrome,can be as a fluorescent model drug.
Uses	Coumarin 6 has been used as a hydrophobic fluorescent dye in block copolymer (BCP)-based micelle based drug delivery studies in glioma cell lines in combination with flufenamic acid (FA) based nanoprodrug uptake in glioma cells in poly(lactic-co-glycolic acid) (PLGA) based elvitegravir nanoprodrug uptake studies
Definition	ChEBI: Coumarin 6 is a member of 7-aminocoumarins. It has a role as a fluorochrome.
General Description	Coumarin 6 as fluorescence lifetime standards in fluorescence spectroscopy was reported to be the most stable for performing lifetime experiments.

Coumarin 6 Preparation Products And Raw materials

Raw materials

Ethanol-->Sodium hydroxide-->Ethyl acetate-->Methanol-->Dichloromethane-->Acetic acid-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Phosphorus oxychloride-->Chloroform-->Potassium hydroxide-->Isopropyl alcohol-->Ethyl cyanoacetate-->1-Butanol-->Piperidine-->1,2-Dichlorobenzene-->3-Diethylaminophenol-->2-Aminobenzenethiol-->3-Methoxypropylamine

Coumarin Coumarin 6 3-(2-BENZOTHIAZOLYL)-7-(DIETHYLAMINO)COUMARIN-4-CARBOXYLIC ACID 10-(2-BENZOTHIAZOLYL)-2,3,6,7-TETRAHYDRO-1H,5H, 11H[1] BENZOPYRANO[6,7,8-IJ]QUINOLIZIN-11-ONE Benzothiazole Lithium bis(trimethylsilyl)amide 2-Mercaptobenzothiazole Coumarine311 Dihydrocoumarin 4-Methylumbelliferone CoumarinDerivatives 10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-(1)benzopyropyrano(6,7-8-I,j)quinolizin-11-one 2,2'-Dithiobis(benzothiazole) 7-HYDROXY-3-(4'-HYDROXYPHENYL)-4-PHENYL COUMARIN 7-DIETHYLAMINO-3-((((2-IODOACETAMIDO)ETHYL) AMINO)CARBONYL)COUMARIN Cyclamic acid Molasses DICUMAROL

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