1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Basic information
Product Name:1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE
Synonyms:DII (DYE);DII;DIL;DILC18(3);D 282;D 282 (DYE);1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE;1,1-DIOCTADECYL-3,3,3,3-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE
CAS:41085-99-8
MF:C59H97ClN2O4
MW:933.87
EINECS:
Product Categories:Cyanine
Mol File:41085-99-8.mol
1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Structure
1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Chemical Properties
Melting point 68 °C (dec.)(lit.)
storage temp. 2-8°C
solubility DMF: soluble
form crystals or powder
color Burgundy to purples-violet
λmax549 nm
BRN 8251870
Biological ApplicationsDetecting cell fusion,cell adhesion,cell migration,cell proliferation; membrane fusion assay; exocytosis and/or endocytosis assay
InChIKeyJVXZRNYCRFIEGV-UHFFFAOYSA-M
CAS DataBase Reference41085-99-8
Safety Information
Safety Statements 22-24/25
WGK Germany 3
8
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Usage And Synthesis
Uses1,1'-Di-n-octadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate is used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.
Uses1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is a lipophilic dye used to record membrane voltage for fluidity studies. This retrograde stain is useful in staining neurons?in vitro?and?in vivo?because the stain is relatively nontoxic to cell bodies and the dye is retained in neurons. In addition, 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is an ideal retrograde and anterograde tracer to label the processes as well as the cell bodies of cultured neurons.
Uses1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in fluorescent labelling of mesenchymal stem cells (MSCs)?and cerebral cortex. It has also been used in electromyogram (EMG) to determine awake and anesthetized states in mice.
General DescriptionDiI is a Dye Aye, a chemical with CAS number 41085-99-8. It is a fluorescent lipophilic cationic indocarbocyanine dye, which is usually made as a perchlorate salt. Mostly used for scientific staining purposes, such as single molecule imaging, fate mapping and neuronal tracing (as DiI is retained in the lipid bilayers).
Biochem/physiol ActionsLipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.
1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Preparation Products And Raw materials
3,3'-DIHEPTYLOXACARBOCYANINE IODIDE 3,3'-DIPROPYLTHIADICARBOCYANINE IODIDE 3,3'-DIHEXYLOXACARBOCYANINE IODIDE TMA-DPH Hexacyanine 2 DIO 3,3'-DIPENTYLOXACARBOCYANINE IODIDE BIS-(1,3-DIETHYLTHIOBARBITURIC ACID)TRIMETHINE OXONOL 3 3'-DIETHYLOXACARBOCYANINE IODIDE 98 OCTADECYLAMINE HYDROCHLORIDE 5,5'-DIBROMO-1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE 1-Ethyl-2-methylene-3,3-dimethylindoline N-dodecyl-N-methylaniline 1,1'-DIHEXADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Glutacondianil hydrochloride 1-ICOSYL-2-[(E)-3-(1-ICOSYL-3,3-DIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)-1-PROPENYL]-3,3-DIMETHYL-3H-INDOLIUM PERCHLORATE 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE ('DII'; DIIC18(3))

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