ANAGYRINE

ANAGYRINE Basic information
Product Name:ANAGYRINE
Synonyms:ANAGYRINE;RHOMBININE;3,4,5,6-Tetradehydrospartein-2-one;7,14-Methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one, 7,7a,8,9,10,11,13,14-octahydro-, [7R-(7alpha,7abeta,14alpha)]-;Anagyrin;Monolupin;Monolupine;Rhombinin
CAS:486-89-5
MF:C15H20N2O
MW:244.33
EINECS:
Product Categories:Alkaloids
Mol File:486-89-5.mol
ANAGYRINE Structure
ANAGYRINE Chemical Properties
alpha D25 -168° (c = 4.8 in ethanol)
Boiling point bp4 210-215°; bp12 260-270°
density 1.22±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 1.6280 (estimate)
storage temp. Store at -20°C
solubility DMSO: soluble,Methanol: soluble
form Cryst.
pka9.71±0.20(Predicted)
CAS DataBase Reference486-89-5
Safety Information
MSDS Information
ANAGYRINE Usage And Synthesis
DescriptionAn amorphous alkaloid isolated from Thermopsis rhombifolia (Watt), Richards, and also present in Lupinus macounii Rydb. The base forms a perchlorate, m.p. 313°C and a picrate, m.p. 253°C. On catalytic hydrogenation it yields the octahydro derivative, b.p. l40°CjO.2 mm which also forms a perchlorate, m.p. 213°C; [α]D - 40.9° (H20).
UsesAnagyrine is a naturally occuring alkaloid found in Genista vuralli, which displays antimicrobial activity.
targetAntifection
ReferencesManske, Marion., Can. J. Res., 20B, 265 (1942)
Manske, Marion., ibid, 21B, 144 (1943)
ANAGYRINE Preparation Products And Raw materials
Preparation Products(7R,7aR,14R,14aS)-Dodecahydro-7,14-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine-4-one
Xanthiazone L-Hyoscyamine daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one DIETHYL-PIPERIDIN-3-YLMETHYL-AMINE ANAGYRINE Anagyrine monohydrobromide 2-(1-ISOBUTYLPIPERIDIN-2-YL)ETHANAMINE 3-Acetylaminomethyl piperidine Caulophylline N,N-Dimethylaminopropyl acrylamide 1-Butyl-2(1H)-pyridinone Cytisine 1-(PIPERIDIN-3-YLMETHYL)PIPERIDINE thermospine 3-(2-ethylpiperidin-1-yl)propan-1-amine 1-(3-AMINOPROPYL)-2-PIPECOLINE CHEMBRDG-BB 4014886

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